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ethyl 4-isothiocyanatobutanoate

Known as: 4-isothiocyanatobutanoic acid ethyl ester, E-4IB cpd, E-4IB 
 
National Institutes of Health

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2 relations

Broader (2)

ButyratesIsothiocyanates

Papers overview

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2009
2009
Administration of isothiocyanate (E-4IB) and cisplatin leads to altered signalling and lysosomal export in human ovarian carcinoma sensitive- and cisplatin-resistant cells.
The aim of this study was to compare the effect of a new synthetic isothiocyanate derivative, ethyl 4-isothiocyanatobutanoate (E… Expand
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2008
2008
Antibacterial and mutagenic activities of new isothiocyanate derivatives
Nine newly synthetized isothiocyanate derivatives were demonstrated to posses antibacterial and genotoxic activitiesin vitro. 4… Expand
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2007
2007
Isothiocyanate E-4IB induces MAPK activation, delayed cell cycle transition and apoptosis.
INTRODUCTION Epidemiologic studies point towards a significant correlation between the dietary intake of isothiocyanate… Expand
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2006
2006
Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1
The effect of synthetic isothiocyanate ethyl-4-isothiocyanatobutanoate (E-4IB) on survival of mismatch repair-proficient TK6 and… Expand
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2006
2006
Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations
A new synthetic isothiocyanate (ITC) derivative, ethyl 4-isothiocyanatobutanoate (E-4IB), appeared to be an effective modulator… Expand
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2005
2005
Enhanced sensitivity of human ovarian carcinoma cell lines A2780 and A2780/CP to the combination of cisplatin and synthetic isothiocyanate ethyl 4-isothiocyanatobutanoate.
Naturally occurring and synthetic isothiocyanates (ITCs) are known as chemopreventive agents. The present study shows a new… Expand
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2002
2002
Immunotoxic and cancerostatic effects of ethyl-4-isothiocyanatobutanoate in female Lewis rats with implanted fibrosarcoma.
Isothiocyanates (ITCs) have been isolated from plants. Naturally occurring and synthetic ITCs are known as effective… Expand
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2000
2000
Immunotoxicity of ethyl-4-isothiocyanatobutanoate in male Wistar rats.
The immunotoxicity of ethyl-4-isothiocyanatobutanoate (E-4IB) using different immuno-pathological parameters and immune function… Expand
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1997
1997
Cytotoxic activity of ethyl-4-isothiocyanatobutanoate and its synthetic derivatives on HeLa cells
 
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1993
1993
Ethyl 4-isothiocyanatobutanoate--antiproliferative activity in vitro and in vivo.
A new isothiocyanate (ITC) derivate ethyl 4-isothiocyanatobutanoate (E-4IB) induces an immediate dose-dependent inhibitory action… Expand
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