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ethyl 4-isothiocyanatobutanoate

Known as: 4-isothiocyanatobutanoic acid ethyl ester, E-4IB cpd, E-4IB 
National Institutes of Health

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2 relations

Broader (2)

ButyratesIsothiocyanates

Papers overview

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2009
2009
Administration of isothiocyanate (E-4IB) and cisplatin leads to altered signalling and lysosomal export in human ovarian carcinoma sensitive- and cisplatin-resistant cells.
The aim of this study was to compare the effect of a new synthetic isothiocyanate derivative, ethyl 4-isothiocyanatobutanoate (E… 
2008
2008
Antibacterial and mutagenic activities of new isothiocyanate derivatives
Nine newly synthetized isothiocyanate derivatives were demonstrated to posses antibacterial and genotoxic activitiesin vitro. 4… 
2007
2007
Isothiocyanate E‐4IB induces MAPK activation, delayed cell cycle transition and apoptosis
Abstract.  Introduction: Epidemiologic studies point towards a significant correlation between the dietary intake of… 
2006
2006
Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1
The effect of synthetic isothiocyanate ethyl-4-isothiocyanatobutanoate (E-4IB) on survival of mismatch repair-proficient TK6 and… 
2006
2006
Sensitisation for cisplatin-induced apoptosis by isothiocyanate E-4IB leads to signalling pathways alterations
A new synthetic isothiocyanate (ITC) derivative, ethyl 4-isothiocyanatobutanoate (E-4IB), appeared to be an effective modulator… 
2005
2005
Enhanced sensitivity of human ovarian carcinoma cell lines A2780 and A2780/CP to the combination of cisplatin and synthetic isothiocyanate ethyl 4-isothiocyanatobutanoate.
Naturally occurring and synthetic isothiocyanates (ITCs) are known as chemopreventive agents. The present study shows a new… 
2002
2002
Immunotoxic and cancerostatic effects of ethyl-4-isothiocyanatobutanoate in female Lewis rats with implanted fibrosarcoma.
2000
2000
Immunotoxicity of ethyl-4-isothiocyanatobutanoate in male Wistar rats.
1997
1997
Cytotoxic activity of ethyl-4-isothiocyanatobutanoate and its synthetic derivatives on HeLa cells
1993
1993
Ethyl 4‐isothiocyanatobutanoate—antiproliferative activity in vitro and in vivo
A new isothiocyanate (ITC) derivate ethyl 4-isothiocyanatobutanoate (E-4IB) induces an immediate dose-dependent inhibitory action… 
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