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estromustine

Known as: estrone 17 beta-3-N-bis(2-chloroethyl)carbamate 
 
National Institutes of Health

Papers overview

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2000
2000
Determination of estramustine phosphate and its metabolites estromustine, estramustine, estrone and estradiol in human plasma by liquid chromatography with fluorescence detection and gas…
Bioanalytical methods for the determination of estramustine phosphate by liquid chromatography and its four main metabolites… Expand
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1998
1998
Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue.
Estracyt (EMP) has been used for the treatment of hormone refractory prostate cancer for many years. Recently, new data from… Expand
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1996
1996
Potentiation by estramustine of the cytotoxic effect of vinblastine and doxorubicin in prostatic tumor cells.
The effects of combining estramustine (EM) with vinblastine (VLB) or doxorubicin (DOX) on cellular uptake, cellular retention and… Expand
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Review
1995
Review
1995
Estramustine Phosphate Sodium
SummarySynopsisEstramustine phosphate sodium (estramustine phosphate), a unique antitumour agent, is selectively taken up by… Expand
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1995
1995
Purification of estramustine-binding protein and production of monoclonal antibodies to its different components.
Estramustine-binding protein (EMBP) is a heterodimeric 46-kDa glycoprotein that is secreted from the prostate. Upon reductive… Expand
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1993
1993
Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans.
Estraumustine phosphate (EMP), a cytotoxic drug used in the treatment of prostatic carcinoma, has been shown to exert cytotoxic… Expand
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1992
1992
Molecular conformation of estramustine and two analogues.
The crystal and molecular structures of estramustine and two of its analogues have been determined by X-ray crystallographic… Expand
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1991
1991
Accumulation of estramustine and estromustine in adipose tissue of rats and humans
SummaryThe tissue distribution of estramustine and estromustine, two cytotoxic lipophilic metabolites of estramustine phosphate… Expand
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1988
1988
Uptake of estramustine phosphate (estracyt) metabolites in prostatic cancer.
Plasma and tumour concentrations of estramustine, estromustine, estradiol and estrone, the major metabolites of estramustine… Expand
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1984
1984
Pharmacokinetics of estramustine phosphate (Estracyt®) in prostatic cancer patients
SummaryThe pharmacokinetics of estramustine phosphate (EMP) was studied in five prostatic cancer patients given single i.v. and… Expand
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