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estromustine

Known as: estrone 17 beta-3-N-bis(2-chloroethyl)carbamate 
National Institutes of Health

Papers overview

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2004
2004
Accumulation of estramustine and estromustine in adipose tissue of rats and humans
SummaryThe tissue distribution of estramustine and estromustine, two cytotoxic lipophilic metabolites of estramustine phosphate… Expand
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2000
2000
Determination of estramustine phosphate and its metabolites estromustine, estramustine, estrone and estradiol in human plasma by liquid chromatography with fluorescence detection and gas…
Bioanalytical methods for the determination of estramustine phosphate by liquid chromatography and its four main metabolites… Expand
1998
1998
Differential uptake of estramustine phosphate metabolites and its correlation with the levels of estramustine binding protein in prostate tumor tissue.
Estracyt (EMP) has been used for the treatment of hormone refractory prostate cancer for many years. Recently, new data from… Expand
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1996
1996
Potentiation by estramustine of the cytotoxic effect of vinblastine and doxorubicin in prostatic tumor cells
The effects of combining estramustine (EM) with vinblastine (VLB) or doxorubicin (DOX) on cellular uptake, cellular retention and… Expand
Review
1995
Review
1995
Estramustine Phosphate Sodium
SummarySynopsisEstramustine phosphate sodium (estramustine phosphate), a unique antitumour agent, is selectively taken up by… Expand
1993
1993
Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans.
Estraumustine phosphate (EMP), a cytotoxic drug used in the treatment of prostatic carcinoma, has been shown to exert cytotoxic… Expand
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1992
1992
Molecular conformation of estramustine and two analogues.
The crystal and molecular structures of estramustine and two of its analogues have been determined by X-ray crystallographic… Expand
1988
1988
Uptake of estramustine phosphate (estracyt) metabolites in prostatic cancer.
Plasma and tumour concentrations of estramustine, estromustine, estradiol and estrone, the major metabolites of estramustine… Expand
1988
1988
Expression of an estramustine-binding associated protein in human lung cancer cell lines.
Estramustine-binding protein has previously been demonstrated in normal rat prostatic tissue, in normal human prostate epithelium… Expand
1985
1985
Effects of human chorionic gonadotrophin, oestradiol and estromustine on testicular blood flow in hypophysectomized rats.
The effects of human chorionic gonadotrophin (hCG), eostradiol benzoate (E2) and estromustine (Eo) on testicular and prostatic… Expand
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