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estradiol mustard

Known as: p-(N,N-bis(2-chloroethyl)amino)phenylacetic acid 17-beta-estradiol diester 
A conjugate of two agents, estradiol and an alkylating mustard (usually mechlorethamine or non-nitrogen mustard). Estramustine is one such agent (see… Expand
National Institutes of Health

Papers overview

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2006
2006
The effects of four new synthetic bis-β-chloroethylamine-containing estrogens and known cytostatic agents chlorophenacyl and… Expand
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Highly Cited
1985
Highly Cited
1985
Estramustine phosphate (0.01 to 0.5 mM), an estradiol mustard derivative used in the therapy of prostatic carcinoma, inhibited… Expand
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Review
1983
Review
1983
Antiestrogens (Tamoxifen) are used for the treatment of breast cancer. However these compounds are also weak estrogens that may… Expand
1976
1976
Estradiol mustard (EM) is the 3,17β‐diester of estradiol‐17β (E2) with the nitrogen mustard derivative chlorphenacyl. The ability… Expand
1975
1975
The effects of the following cancer chemotherapeutic agents on serum hormonal levels, estrous cycles, and endocrine organs were… Expand
1974
1974
1974
1974
The ability of estradiol mustard to bind receptors in rat uterine cytosol (as measured by the inhibition of binding of estradiol… Expand
1973
1973