FAQ

estradiol mustard

Known as: p-(N,N-bis(2-chloroethyl)amino)phenylacetic acid 17-beta-estradiol diester 
A conjugate of two agents, estradiol and an alkylating mustard (usually mechlorethamine or non-nitrogen mustard). Estramustine is one such agent (see… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2005
012319732005

Related topics

Related topics

2 relations

Narrower (1)

NSC 112259

Broader (1)

Nitrogen Mustard Compounds

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
estradiol mustard
Nitrogen Mustard Compounds
NSC 112259

Papers overview

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2005
2005
[Study on the inclusion interaction of water-soluble p-(N,N-dimethylamino)-calix[8]arene with diphenylamine-4-sulfonic sodium salt].
The inclusion interaction of water-soluble p-(N,N-dimethylaminomethyl)-calix[8]arene with diphenylamine-4-sulfonic acid sodium… (More)
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2003
2003
New fluorescent probes for visual proteins. Part II. 5-(Oxo)penta-2,4-dienyl-p-(N,N-dimethylamino)benzoate.
A new dual-fluorescent compound, 5-(oxo)penta-2,4-dienyl-p-(N,N-dimethylamino)benzoate (1), a derivative of dimethylaminobenzoic… (More)
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2000
2000
Effects of synthetic bis-β-chloroethylamine estrogen derivatives on proliferation of skin sarcoma cells
The effects of four new synthetic bis-β-chloroethylamine-containing estrogens and known cytostatic agents chlorophenacyl and… (More)
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1985
1985
Effect of estramustine phosphate on the assembly of isolated bovine brain microtubules and fast axonal transport in the frog sciatic nerve.
Estramustine phosphate (0.01 to 0.5 mM), an estradiol mustard derivative used in the therapy of prostatic carcinoma, inhibited… (More)
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1978
1978
Bioassay of Estradiol Mustard for Possible Carcinogenicity (CAS No. 22966-79-6).
  • National Cancer Institute carcinogenesis…
  • 1978
A bioassay of the experimental anticancer drug estradiol mustard for possible carcinogenicity was conducted by administering the… (More)
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1976
1976
Affinity of estradiol mustard for estrogen receptors and its enzymatic degradation in uterine and breast cancer cytosols.
Estradiol mustard (EM) is the 3,17beta-diester of estradiol-17beta (E2) with the nitrogen mustard derivative chlorphenacyl. The… (More)
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1976
1976
Absence of carcinogenic effects of Estradiol mustard (NSC-112259) in rats
Estradiol mustard (NSC 112259) was subcutaneously injected to female Sprague-Dawley-rats in weekly doses of 10 and 20 mg/kg up to… (More)
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1975
1975
Effects of cancer chemotherapeutic agents on endocrine organs and serum levels of estrogens, progesterone, prolactin, and luteinizing hormone.
The effects of the following cancer chemotherapeutic agents on serum hormonal levels, estrous cycles, and endocrine organs were… (More)
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1974
1974
Estrogen receptor interaction with the antitumor agent estradiol mustard.
 
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1973
1973
Estradiol mustard (NSC-112259)--clinical brochure.
 
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