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estradiol mustard
Known as:
p-(N,N-bis(2-chloroethyl)amino)phenylacetic acid 17-beta-estradiol diester
A conjugate of two agents, estradiol and an alkylating mustard (usually mechlorethamine or non-nitrogen mustard). Estramustine is one such agent (see…
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National Institutes of Health
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Related topics
Related topics
2 relations
Narrower (1)
NSC 112259
Broader (1)
Nitrogen Mustard Compounds
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Effects of synthetic bis-β-chloroethylamine estrogen derivatives on proliferation of skin sarcoma cells
A. V. Semeikin
,
V. M. Rzheznikov
,
E. Mayatskaya
,
Z. Smirnova
Bulletin of experimental biology and medicine
2000
Corpus ID: 23878691
The effects of four new synthetic bis-β-chloroethylamine-containing estrogens and known cytostatic agents chlorophenacyl and…
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Highly Cited
1985
Highly Cited
1985
Effect of estramustine phosphate on the assembly of isolated bovine brain microtubules and fast axonal transport in the frog sciatic nerve.
M. Kanje
,
J. Deinum
,
M. Wallin
,
P. Ekström
,
A. Edström
,
B. Hartley‐åsp
Cancer Research
1985
Corpus ID: 18677483
Estramustine phosphate (0.01 to 0.5 mM), an estradiol mustard derivative used in the therapy of prostatic carcinoma, inhibited…
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Review
1983
Review
1983
Guide-lines in the design of new antiestrogens and cytotoxic-linked estrogens for the treatment of breast cancer.
G. Leclercq
,
N. Devleeschouwer
,
J. Heuson
Journal of Steroid Biochemistry
1983
Corpus ID: 39650569
1976
1976
Affinity of estradiol mustard for estrogen receptors and its enzymatic degradation in uterine and breast cancer cytosols
G. Leclercq
,
M. Deboel
,
J. Heuson
International Journal of Cancer
1976
Corpus ID: 34898822
Estradiol mustard (EM) is the 3,17β‐diester of estradiol‐17β (E2) with the nitrogen mustard derivative chlorphenacyl. The ability…
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1975
1975
Effects of cancer chemotherapeutic agents on endocrine organs and serum levels of estrogens, progesterone, prolactin, and luteinizing hormone.
E. Kuo
,
H. Esber
,
D. Taylor
,
A. Bogdén
Cancer Research
1975
Corpus ID: 928072
The effects of the following cancer chemotherapeutic agents on serum hormonal levels, estrous cycles, and endocrine organs were…
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1974
1974
Estradiol mustard (NSC-112259) and phenester (NSC-116785): possible mediation of action by estrogen binding protein.
Everson Rb
,
Turnell Rw
,
Wittliff Jl
,
Hall Tc
1974
Corpus ID: 83529880
The ability of estradiol mustard to bind receptors in rat uterine cytosol (as measured by the inhibition of binding of estradiol…
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1974
1974
Estrogen receptor interaction with the antitumor agent estradiol mustard.
R. E. Shepherd
,
K. Huff
,
W. McGuire
Journal of the National Cancer Institute
1974
Corpus ID: 20576549
1973
1973
Estradiol mustard (NSC-112259)--clinical brochure.
E. Vollmer
,
D. Taylor
,
I. Masnyk
,
D. Cooney
,
B. Levine
,
C. Piczak
Cancer chemotherapy reports. Part 3
1973
Corpus ID: 44998907
1972
1972
Alkylating analogs of peptide hormones. 2. Synthesis and properties of p-(N,N-bis(2-chloroethyl)amino)phenylbutyryl derivatives of angiotensin II.
T. B. Paiva
,
A. Paiva
,
R. Freer
,
J. Stewart
Journal of Medicinal Chemistry
1972
Corpus ID: 13052490
1967
1967
Research on compounds with antiblastic activity. XXX. p-(N,N-bis-(beta-chloroethyl)amino)benzylidene derivatives of some cyclopentanones.
R. Giuliano
,
A. Ermili
,
M. Artico
,
E. Grundmann
,
R. Bierling
,
D. Steinhoff
Il Farmaco; edizione scientifica
1967
Corpus ID: 10445613
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