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In fetal sheep during late gestation sulfoconjugated estrogens in plasma reach a concentration 40-100 times greater than… Expand Objective: The hormonal interactions between the placenta and the fetal hypothalamus-pituitary adrenal (HPA) axis are reviewed… Expand Using recombinant sulfotransferases (SULTs) expressed in E. coli, beta-estradiol (E2) sulfonation was examined to determine which… Expand In sheep, the fetal hypothalamus-pituitary-adrenal axis plays a central role in the initiation of parturition. We have reported… Expand Concern about possible adverse effects caused by the inadvertent exposure of humans and wildlife to endocrine-active chemicals… Expand Estrogen sulfates are quantitatively the most important form of circulating estrogens during the menstrual cycle and in the post… Expand Estrogen-responsive human cells derived from a specimen of well differentiated endometrial adenocarcinoma (Ishikawa line) were… Expand Estrogen sulfatase (ES) and estrogen sulfotransferase (ESFT) activities were measured in a group of primary breast tumors. The… Expand The ability of estrogen conjugates to act as estrogen precursors in mammary tumor cells has been examined. One hour after… Expand Rates of entry of estrone ( E1, estradiol (E2), progesterone (P), 20αdihydroprogesterone (20αDHP), estrone sulfate (E1S) and… Expand