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estradiol-3-glucuronide
Known as:
beta-D-Glucopyranosiduronic acid, (17 beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Estradiol
analogs & derivatives
estradiol-17 beta-glucuronide
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain
S. S. Lewis
,
M. Hutchinson
,
M. Frick
,
Y. Zhang
,
L. Watkins
Brain, Behavior, and Immunity
2015
Corpus ID: 205864355
We have recently shown that several classes of glucuronide metabolites, including the morphine metabolite morphine-3-glucuronide…
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2014
2014
Comparing the glucuronidation capacity of the feline liver with substrate-specific glucuronidation in dogs.
C. D. van Beusekom
,
J. Fink-Gremmels
,
J. Schrickx
Journal of veterinary pharmacology and…
2014
Corpus ID: 24237613
This study aimed to assess the overall glucuronidation capacity of cats, using prototypic substrates identified for human UDP…
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2011
2011
Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2)
Vandana Megaraj
,
Tianyong Zhao
,
C. Paumi
,
P. Gerk
,
R. Kim
,
M. Vore
Pharmacogenetics and genomics
2011
Corpus ID: 25108881
Background Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide…
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Highly Cited
2008
Highly Cited
2008
Effect of the β‐glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP‐glucuronosyltransferases
L. Oleson
,
M. Court
The Journal of pharmacy and pharmacology
2008
Corpus ID: 33409809
Glucuronidation studies using microsomes and recombinant uridine diphosphoglucuronosyltransferases (UGTs) can be complicated by…
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2008
2008
In vivo chronic exposure to heroin or naltrexone selectively inhibits liver microsome formation of estradiol-3-glucuronide in the rat.
L. Antonilli
,
Valentina Brusadin
,
M. Milella
,
F. Sobrero
,
A. Badiani
,
P. Nencini
Biochemical pharmacology
2008
Corpus ID: 22227838
We have previously found that repeated exposure to heroin reduces liver synthesis of morphine-3-glucuronide (M3G) and increases…
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2004
2004
Metabolism of opioids is altered in liver microsomes of sickle cell transgenic mice.
S. Nagar
,
R. Remmel
,
R. Hebbel
,
C. Zimmerman
Drug metabolism and disposition: the biological…
2004
Corpus ID: 8266062
Pain in sickle cell anemia (SCA) is clinically managed with opioid analgesics. There are reports that SCA patients tolerate high…
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Highly Cited
2003
Highly Cited
2003
The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases.
M. Soars
,
B. Ring
,
S. Wrighton
Drug metabolism and disposition: the biological…
2003
Corpus ID: 14909285
Traditionally, the Michaelis-Menten equation has been used to determine kinetic parameters for in vitro glucuronidation assays…
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2002
2002
Sensitive liquid chromatographic method using fluorescence detection for the determination of estradiol 3- and 17-glucuronides in rat and human liver microsomal incubations: formation kinetics.
K. Alkharfy
,
R. Frye
Journal of chromatography. B, Analytical…
2002
Corpus ID: 34777968
We have developed a sensitive and specific HPLC-fluorescence assay for the determination of estradiol-3-glucuronide and estradiol…
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Highly Cited
1978
Highly Cited
1978
Metabolism of androgens and estrogens by human fecal microorganisms.
P. Lombardi
,
B. Goldin
,
E. Boutin
,
S. Gorbach
Journal of steroid biochemistry
1978
Corpus ID: 31574972
Abstract Modifications of androgens and estrogens were observed in incubations with mixed human fecal cultures. Both oxidative…
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1977
1977
In vitro and in vivo studies on the metabolism of estrogens and their sulfates in guinea pigs.
R. Hobkirk
,
D. Freeman
,
P. R. Harvey
,
M. Nilsen
,
B. Jennings
Canadian journal of biochemistry
1977
Corpus ID: 43704895
Labelled estradiol-17 beta(E2) or estrone (E1), when incubated with guinea pig liver slices, is metabolized by two main pathways…
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