estradiol-3-glucuronide

Known as: beta-D-Glucopyranosiduronic acid, (17 beta)-17-hydroxyestra-1,3,5(10)-trien-3-yl 
 
National Institutes of Health

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Broader (1)

Estradiol
analogs & derivativesestradiol-17 beta-glucuronide

Papers overview

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2015
2015
Select steroid hormone glucuronide metabolites can cause toll-like receptor 4 activation and enhanced pain
We have recently shown that several classes of glucuronide metabolites, including the morphine metabolite morphine-3-glucuronide… (More)
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2014
2014
Comparing the glucuronidation capacity of the feline liver with substrate-specific glucuronidation in dogs.
This study aimed to assess the overall glucuronidation capacity of cats, using prototypic substrates identified for human UDP… (More)
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2011
2011
Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2).
BACKGROUND Multidrug resistance-associated protein 2 (MRP2; ABCC2) mediates the biliary excretion of glutathione, glucuronide… (More)
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2008
2008
In vivo chronic exposure to heroin or naltrexone selectively inhibits liver microsome formation of estradiol-3-glucuronide in the rat.
We have previously found that repeated exposure to heroin reduces liver synthesis of morphine-3-glucuronide (M3G) and increases… (More)
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2008
2008
Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.
Glucuronidation studies using microsomes and recombinant uridine diphosphoglucuronosyltransferases (UGTs) can be complicated by… (More)
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2005
2005
DIFFERENTIAL UGT 1 A 1 INDUCTION BY CHRYSIN IN PRIMARY HUMAN HEPATOCYTES AND HEPG 2 CELLS
Chrysin, a dietary flavonoid, has been shown to markedly induce UGT1A1 expression and activity in HepG2 and Caco-2 cell lines… (More)
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2004
2004
Metabolism of opioids is altered in liver microsomes of sickle cell transgenic mice.
Pain in sickle cell anemia (SCA) is clinically managed with opioid analgesics. There are reports that SCA patients tolerate high… (More)
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Highly Cited
2003
Highly Cited
2003
The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases.
Traditionally, the Michaelis-Menten equation has been used to determine kinetic parameters for in vitro glucuronidation assays… (More)
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2002
2002
Sensitive liquid chromatographic method using fluorescence detection for the determination of estradiol 3- and 17-glucuronides in rat and human liver microsomal incubations: formation kinetics.
We have developed a sensitive and specific HPLC-fluorescence assay for the determination of estradiol-3-glucuronide and estradiol… (More)
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1977
1977
In vitro and in vivo studies on the metabolism of estrogens and their sulfates in guinea pigs.
Labelled estradiol-17 beta(E2) or estrone (E1), when incubated with guinea pig liver slices, is metabolized by two main pathways… (More)
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