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establishment of granzyme B localization to T cell secretory granule

Known as: establishment of granzyme B localization in T-lymphocyte secretory granule, establishment of granzyme B localization in T lymphocyte secretory granule, establishment of granzyme B localization in T cell secretory granule 
The directed movement of the protease granzyme B to a location within a secretory granule in a T cell. [GOC:mah]
National Institutes of Health

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granzyme B localization to T cell secretory granule

Papers overview

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2017
2017
Abstract 4587: A human hybrid immuno-oncology construct targeting the TWEAK receptor Fn14 and containing the serine protease granzyme B
Targeting immune effector cells to tumors has recently emerged as a clinically-relevant approach for therapy. The underlying… 
2012
2012
Detection of human and mouse granzyme B activity in cell extracts.
The serine protease granzyme B (GrB) is a key effector molecule in cell-mediated immunity, released by cytotoxic lymphocytes (CLs… 
Highly Cited
2006
Highly Cited
2006
The Cytotoxic Lymphocyte Protease, Granzyme B, Targets the Cytoskeleton and Perturbs Microtubule Polymerization Dynamics*
Granzyme B, a serine protease derived from cytotoxic T lymphocyte (CTL) and Natural Killer (NK) cell granules, plays an important… 
2006
2006
Cell binding, internalization and cytotoxic activity of human granzyme B expressed in the yeast Pichia pastoris.
Granzyme B (GrB) is an apoptosis-inducing protease of cytotoxic lymphocytes. We have investigated intracellular and extracellular… 
Review
2006
Review
2006
Targeting serine proteases in asthma.
Leukocytes and lung structural cells contribute to the pathophysiology of asthma through the production of numerous mediators… 
Highly Cited
2003
Highly Cited
2003
Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice.
We have investigated whether granzyme B (GzmB) is required for effective cytotoxic T lymphocyte (CTL) mediated control of… 
Highly Cited
1998
Highly Cited
1998
Down-regulation of Human Granzyme B Expression by Glucocorticoids
The serine protease granzyme B is an essential component of the granule exocytosis pathway, a major apoptotic mechanism used by… 
1998
1998
Expression and Purification of Enzymatically Active Recombinant Granzyme B in a Baculovirus System
ICE family (caspases), which exist as inactive zymo-Granzyme B (GranB), a serine protease stored in the gens under normal… 
Review
1996
Review
1996
Activation of apoptosis pathways by granzyme B.
Cytotoxic lymphocytes induce apoptosis of target cells by degranulating and releasing the serine protease granzyme B and the pore… 
1994
1994
Expression of granzyme A in salivary gland biopsies from patients with primary Sjögren's syndrome.
OBJECTIVE To determine whether the destruction of salivary gland epithelial cells in Sjögren's syndrome (SS) could be mediated by… 
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