establishment of granzyme B localization to T cell secretory granule

Known as: establishment of granzyme B localization in T-lymphocyte secretory granule, establishment of granzyme B localization in T lymphocyte secretory granule, establishment of granzyme B localization in T cell secretory granule 
The directed movement of the protease granzyme B to a location within a secretory granule in a T cell. [GOC:mah]
National Institutes of Health

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Review
2010
Review
2010
Granzyme A (GzmA) is the most abundant serine protease in killer cell cytotoxic granules. GzmA activates a novel programed cell… (More)
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Highly Cited
2008
Highly Cited
2008
Granzyme A (GzmA) is considered a major proapoptotic protease. We have discovered that GzmA-induced cell death involves rapid… (More)
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2006
2006
Granzyme B, a serine protease derived from cytotoxic T lymphocyte (CTL) and Natural Killer (NK) cell granules, plays an important… (More)
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Highly Cited
2005
Highly Cited
2005
Granzyme B is a major cytotoxic T lymphocyte/natural killer (CTL/NK) granule protease that can activate members of the caspase… (More)
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Highly Cited
2005
Highly Cited
2005
Cytotoxic T lymphocytes eliminate infected and tumor cells mainly by perforin/granzyme-induced apoptosis. Earlier studies… (More)
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Highly Cited
2003
Highly Cited
2003
Cell surface-bound heat shock protein 70 (Hsp70) renders tumor cells more sensitive to the cytolytic attack mediated by natural… (More)
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2001
2001
Autoimmune processes are initiated when tolerance to self-proteins fails to be established or maintained and immune cells are… (More)
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Highly Cited
1999
Highly Cited
1999
Systemic autoimmune diseases are a genetically complex, heterogeneous group of disorders in which the immune system targets a… (More)
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Highly Cited
1996
Highly Cited
1996
Lymphocyte granule-mediated apoptosis is postulated to entail the formation of membrane pores by perforin. Then soluble granzyme… (More)
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Highly Cited
1995
Highly Cited
1995
CYTOTOXIC T lymphocyte (CTL)-mediated cytotoxicity represents the body's major defence against virus-infected and tumorigenic… (More)
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