erythromycin propionate-N-acetylcysteinate

Known as: EPAC 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
051019892018

Papers overview

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Highly Cited
2012
Highly Cited
2012
EPAC proteins are the guanine nucleotide exchange factors that act as the intracellular receptors for cyclic AMP. Two variants of… (More)
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2011
2011
Agonist activation of the small GTPase, RhoA, and its effector Rho kinase leads to down-regulation of smooth muscle (SM) myosin… (More)
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2010
2010
Cell survival and death play critical roles in tissues composed of post-mitotic cells. Cyclic AMP (cAMP) has been known to exert… (More)
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2010
2010
The ability of cancer cells to invade and metastasize is the major cause of death in cancer patients. Autotaxin (ATX) is a… (More)
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2009
2009
Endogenous mediators within the inflammatory milieu play a critical role in directing the scope, duration, and resolution of… (More)
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2008
2008
The prototypical second messenger cAMP is a key regulator of immune and inflammatory responses. Its ability to inhibit… (More)
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2008
2008
Cyclooxygenase-2 (COX-2)-dependent prostaglandin E(2) (PGE(2)) synthesis correlates with the onset of proteinuria and increased… (More)
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2007
2007
The multi-PDZ domain containing protein Na(+)/H(+) Exchanger Regulatory Factor 1 (NHERF1) binds to Na(+)/H(+) exchanger 3 (NHE3… (More)
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2006
2006
Dopamine increases lung fluid clearance. This is partly due to activation of basolateral Na-K-ATPase. However, activation of Na-K… (More)
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2004
2004
Type 4 cyclic adenosine monophosphate (cAMP) phosphodiesterase (PDE4) inhibitors and other agents that raise intracellular cAMP… (More)
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