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erythromycin A isoxazoline

National Institutes of Health

Papers overview

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2017
2017
BackgroundThe isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric acid (GABA)-gated… Expand
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Highly Cited
2016
Highly Cited
2016
The novel isoxazoline ectoparasiticide, sarolaner, was identified during a lead optimization program for an orally-active… Expand
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2015
2015
A novel series of isoxazoline benzoxaborole small molecules was designed and synthesized for a structure-activity relationship… Expand
2011
2011
A collection of isoxazoles derivatives has been efficiently synthesized in three steps. The oximation reaction of aldehydes… Expand
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Highly Cited
2010
Highly Cited
2010
A structurally unique isoxazoline class compound, A1443, exhibits antiparasitic activity against cat fleas and dog ticks… Expand
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Highly Cited
2009
Highly Cited
2009
A major driving force for the intriguing developments in the field of total synthesis over the past century is the proficiency… Expand
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2006
2006
A series of novel 3-[5-ethyl-2-(2-phenoxy-ethyl)-pyridin]-5-substituted isoxazolines were synthesized via 1,3-dipolar… Expand
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Highly Cited
2005
Highly Cited
2005
Abstract2-Thiouracil-5-sulphonic acidN-(4-acetylphenyl) Amide (1) was reacted with a series of aromatic aldehydes giving… Expand
2004
2004
Analogues of isoxazoline alpha(v)beta(3) antagonist 1 designed to further restrict the four carbon alkyl tether were prepared by… Expand
2003
2003
Factor Xa (fXa) is an important serine protease in the blood coagulation cascade. Inhibition of fXa has emerged as an attractive… Expand