erythromycin A isoxazoline
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BackgroundThe isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric acid (GABA)-gated… Expand The novel isoxazoline ectoparasiticide, sarolaner, was identified during a lead optimization program for an orally-active… Expand A novel series of isoxazoline benzoxaborole small molecules was designed and synthesized for a structure-activity relationship… Expand A collection of isoxazoles derivatives has been efficiently synthesized in three steps. The oximation reaction of aldehydes… Expand A structurally unique isoxazoline class compound, A1443, exhibits antiparasitic activity against cat fleas and dog ticks… Expand A major driving force for the intriguing developments in the field of total synthesis over the past century is the proficiency… Expand A series of novel 3-[5-ethyl-2-(2-phenoxy-ethyl)-pyridin]-5-substituted isoxazolines were synthesized via 1,3-dipolar… Expand Abstract2-Thiouracil-5-sulphonic acidN-(4-acetylphenyl) Amide (1) was reacted with a series of aromatic aldehydes giving… Expand Analogues of isoxazoline alpha(v)beta(3) antagonist 1 designed to further restrict the four carbon alkyl tether were prepared by… Expand Factor Xa (fXa) is an important serine protease in the blood coagulation cascade. Inhibition of fXa has emerged as an attractive… Expand