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eprosartan

Known as: Éprosartan, (e)-2-Butyl-1-(P-carboxybenzyl)-alpha-2-thenylimidazole-5-acrylic acid, 2-Thiophenepropanoic acid, alpha-((2-butyl-1-((4- carboxyphenyl)methyl)-lH-imidazol-5-yl)methylene)-, (E)- 
A competitive and reversible angiotensin II receptor antagonist with anti-hypertensive property. Eprosartan blocks the binding of angiotensin II to… 
National Institutes of Health

Related topics

Related topics

21 relations

Broader (5)

AcrylatesAngiotensin II Type 2 Receptor BlockersAntihypertensive AgentsImidazoles
Angiotensin 2 Receptor Antagonists [MoA]Angiotensin 2 Type 1 Receptor Antagonists [MoA]Congestive heart failureDecreased Blood Pressure [PE]

Narrower (3)

SK&F 108566TevetenTeveten HCT

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Quantitative structure-retention relationships applied to development of liquid chromatography gradient-elution method for the separation of sartans.
2015
2015
Celiac disease-like enteropathy due to antihypertensive therapy with the angiotensin-II receptor type 1 inhibitor eprosartan.
An 83-year-old woman with hypertension received the angiotensin-II receptor type 1 blocker (ARB) eprosartan for more than 10… 
Review
2012
Review
2012
Telmisartan improves insulin sensitivity: a meta-analysis of randomized head-to-head trials.
Highly Cited
2002
Highly Cited
2002
Prorenin-Induced Myocyte Proliferation: No Role for Intracellular Angiotensin II
Cardiomyocytes bind, internalize, and activate prorenin, the inactive precursor of renin, via a mannose 6-phosphate receptor… 
2001
2001
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with…
2001
2001
Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors
Abstract. A comparison was made of the influence of losartan and eprosartan on angiotensin II effects at pre- and postjunctional… 
Review
2001
Review
2001
Renal implications of angiotensin receptor blockers.
2000
2000
Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans.
We have previously reported that hyperglycemia in healthy human subjects increased the renal vasodilator response to the… 
1998
1998
Determination of SK&F 108566 (Teveten) in human plasma by reversed-phase high-performance liquid chromatography.
Highly Cited
1997
Highly Cited
1997
A New Regioselective Synthesis of 1,2,5-Trisubstituted 1H-Imidazoles and Its Application to the Development of Eprosartan.
A new method is presented for the preparation of 1,2-disubstitued-1H-imidazole-5-carboxaldehydes by the reaction of N… 
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