epoxide hydrolase activity

Known as: Epoxide hydrolases [PK], Epoxide hydrolases, (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity 
Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate. [EC:3.1.3.76… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2018
020406019742018

Papers overview

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Highly Cited
2007
Highly Cited
2007
A series of N,N'-disubstituted ureas having a conformationally restricted cis- or trans-1,4-cyclohexane alpha to the urea were… (More)
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2007
2007
The human soluble epoxide hydrolase (sEH; EC 3.3.3.2) is the product of the EXPH2 gene. The sEH catalyzes the addition of a water… (More)
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Highly Cited
2006
Highly Cited
2006
Cytochrome P450 epoxygenases metabolize arachidonic acid to epoxyeicosatrienoic acids (EETs) which are converted to… (More)
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Highly Cited
2006
Highly Cited
2006
Sustained cardiac hypertrophy represents one of the most common causes leading to cardiac failure. There is emerging evidence to… (More)
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Highly Cited
2005
Highly Cited
2005
As of 2004, >73 million people were prescribed antiinflammatory medication. Despite the extensive number of current products… (More)
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Highly Cited
2005
Highly Cited
2005
We previously reported that laminar flow activates peroxisome proliferator-activated receptor gamma (PPARgamma) in vascular… (More)
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Highly Cited
2005
Highly Cited
2005
The soluble epoxide hydrolase (sEH) metabolizes vasodilatory epoxyeicosatrienoic acids (EETs) to their di-hydroxy derivatives. We… (More)
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Highly Cited
2003
Highly Cited
2003
The gene EPXH2 encodes for the soluble epoxide hydrolase (sEH), an enzyme involved in the regulation of cardiovascular and renal… (More)
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Highly Cited
2002
Highly Cited
2002
Epoxyeicosatrienoic acids (EETs) have antihypertensive properties and play a part in the maintenance of renal microvascular… (More)
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Highly Cited
2000
Highly Cited
2000
The cytochrome P450-derived epoxyeicosatrienoic acids (EETs) have potent effects on renal vascular reactivity and tubular sodium… (More)
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