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epithelial sodium channel

Known as: Sodium Channel, Epithelial, ENaC (Epithelial Na+ Channel), Sodium Channels, Epithelial 
Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG… Expand
National Institutes of Health

Papers overview

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Review
2009
Review
2009
Epithelial Na+ channels facilitate the transport of Na+ across high resistance epithelia. Proteolytic cleavage has an important… Expand
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Highly Cited
2009
Highly Cited
2009
Proteinuria and increased renal reabsorption of NaCl characterize the nephrotic syndrome. Here, we show that protein-rich urine… Expand
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Highly Cited
2009
Highly Cited
2009
The mineralocorticoid aldosterone is a major regulator of sodium transport in target epithelia and contributes to the control of… Expand
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Highly Cited
2004
Highly Cited
2004
Liddle's syndrome (pseudoaldosteronism) is an autosomal dominant form of human hypertension characterized by a constellation of… Expand
Highly Cited
2002
Highly Cited
2002
The epithelial sodium channel (ENaC) constitutes the rate-limiting step for sodium absorption across airway epithelia, which in… Expand
Highly Cited
1999
Highly Cited
1999
Sodium homeostasis in terrestrial and freshwater vertebrates is controlled by the corticosteroid hormones, principally… Expand
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Highly Cited
1998
Highly Cited
1998
The epithelial sodium channel (ENaC) is a key element for the maintenance of sodium balance and the regulation of blood pressure… Expand
Highly Cited
1997
Highly Cited
1997
The recently defined DEG/ENaC superfamily of sodium channels includes subunits of the amiloride-sensitive epithelial sodium… Expand
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Highly Cited
1994
Highly Cited
1994
The highly selective amiloride-sensitive epithelial sodium channel is formed of three homologous subunits termed alpha-, beta… Expand
Highly Cited
1993
Highly Cited
1993
THE epithelial amiloride-sensitive sodium channel constitutes the rate limiting step for sodium reabsorbtion by the epithelia… Expand