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epipolythiodiketopiperazine

National Institutes of Health

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Piperazines

Papers overview

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2020
2020
Epipolythiodiketopiperazine and trichothecene derivatives from the NaI-containing fermentation of marine-derived Trichoderma cf. brevicompactum
The marine-derived fungus Trichoderma sp. TPU199 (cf. Trichodermabrevicompactum) produces pretrichodermamide A (1) and gliovirin… 
2018
2018
Genome-based deletion analysis in Aspergillus terreus reveals the acetylaranotin bis-thiomethyltransferase gene.
2017
2017
Enantioselective Synthesis of (−)-Acetylapoaranotin
The first enantioselective total synthesis of the epipolythiodiketopiperazine (ETP) natural product (−)-acetylapoaranotin (3) is… 
2016
2016
The Epipolythiodiketopiperazine Gene Cluster in Claviceps purpurea: Dysfunctional Cytochrome P450 Enzyme Prevents Formation of the Previously Unknown Clapurines
Claviceps purpurea is an important food contaminant and well known for the production of the toxic ergot alkaloids. Apart from… 
Highly Cited
2015
Highly Cited
2015
Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids
Conspectus Natural products chemistry has historically been the prime arena for the discovery of new chemical transformations and… 
2014
2014
Part I. Synthetic investigations of heterocyclic natural and unnatural compounds Part II. New approach to latent fingerprint detection on paper
........................................................................................................ VI CHAPTER 1 DIDEMNINS… 
Highly Cited
2013
Highly Cited
2013
Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.
The epipolythiodiketopiperazine (ETP) alkaloids are a highly complex class of natural products with potent anticancer activity… 
2013
2013
Concise Total Synthesis of (+)-Bionectins A and C.
The concise and efficient total synthesis of (+)-bionectins A and C is described. Our approach to these natural products features… 
2011
2011
Inhibition of hypoxia-inducible transcription factor complex with designed epipolythiodiketopiperazine.
Designed small molecule inhibitors of hypoxia-inducible gene expression have potential to become new research tools for molecular… 
Highly Cited
1992
Highly Cited
1992
Inhibition of farnesyl-protein transferase by gliotoxin and acetylgliotoxin.
Ras p21 proteins have been shown to be posttranslationally farnesylated on a specific carboxyterminal cysteine1 ^. Inhibition of… 
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