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epidithiodiketopiperazine

National Institutes of Health

Papers overview

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2013
2013
Hypoxia is a hallmark of solid tumors, is associated with local invasion, metastatic spread, resistance to chemo- and… Expand
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2013
2013
Enzyme quartet: Isolation of the first sulfur-bearing intermediate of the gliotoxin pathway in Aspergillus fumigatus and… Expand
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2013
2013
The downstream targets of hypoxia inducible factor-1 alpha (HIF-1α) play an important role in tumor progression and angiogenesis… Expand
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Highly Cited
2012
Highly Cited
2012
The first total synthesis of the dihydrooxepine-containing epidithiodiketopiperazine (ETP) (-)-acetylaranotin (1) is reported… Expand
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Highly Cited
2011
Highly Cited
2011
Gliotoxin is a virulence factor of the human pathogen Aspergillus fumigatus , the leading cause of invasive aspergillosis. Its… Expand
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Highly Cited
2009
Highly Cited
2009
The fungal metabolite (+)-11,11′-dideoxyverticillin A, a cytotoxic alkaloid isolated from a marine Penicillium sp., belongs to a… Expand
Highly Cited
2009
Highly Cited
2009
Selective blockade of hypoxia-inducible gene expression by designed small molecules would prove valuable in suppressing tumor… Expand
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Highly Cited
2008
Highly Cited
2008
Many of these alkaloids, including the closely related ( )-N(2-phenylethylene)ditryptophenaline (3), contain vicinal quaternary… Expand
2006
2006
[reaction: see text] An unusually bridged epidithiodiketopiperazine, pretrichodermamide A (3), was isolated from the fungus… Expand
1976
1976
A new antibiotic, designated A30641, having in vitro activity against Gram-positive bacteria and fungi has been isolated from a… Expand