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eosinophil differentiation
Known as:
eosinophil cell differentiation
The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil. [GOC:add, GOC:mah]
National Institutes of Health
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Highly Cited
2016
Highly Cited
2016
Role of local eosinophilopoietic processes in the development of airway eosinophilia in prednisone‐dependent severe asthma
R. Sehmi
,
S. Smith
,
+7 authors
P. Nair
Clinical and Experimental Allergy
2016
Corpus ID: 23394795
In severe asthmatics with persistent airway eosinophilia, blockade of interleukin‐5 has significant steroid‐sparing effects and…
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Highly Cited
2015
Highly Cited
2015
The transcription factor XBP1 is selectively required for eosinophil differentiation
Sarah E. Bettigole
,
R. Lis
,
+4 authors
L. Glimcher
Nature Immunology
2015
Corpus ID: 7666096
The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth…
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Highly Cited
2000
Highly Cited
2000
Evidence for Local Eosinophil Differentiation Within Allergic Nasal Mucosa: Inhibition with Soluble IL-5 Receptor1
L. Cameron
,
P. Christodoulopoulos
,
+8 authors
Q. Hamid
Journal of Immunology
2000
Corpus ID: 43788477
Eosinophil differentiation occurs within the bone marrow in response to eosinopoietic cytokines, particularly IL-5. Recently…
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Highly Cited
1998
Highly Cited
1998
Distinct C/EBP functions are required for eosinophil lineage commitment and maturation.
C. Nerlov
,
K. McNagny
,
G. Döderlein
,
E. Kowenz-Leutz
,
T. Graf
Genes & Development
1998
Corpus ID: 32533102
Hematopoietic differentiation involves the commitment of multipotent progenitors to a given lineage, followed by the maturation…
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Highly Cited
1990
Highly Cited
1990
Eosinophilia in transgenic mice expressing interleukin 5
L. Dent
,
M. Strath
,
A. Mellor
,
C. Sanderson
Journal of Experimental Medicine
1990
Corpus ID: 14503851
Experiments in vitro suggest that although interleukin 5 (IL-5) stimulates the late stages of eosinophil differentiation, other…
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Highly Cited
1990
Highly Cited
1990
Regulatory effect of cytokines on eosinophil degranulation.
T. Fujisawa
,
R. Abu-Ghazaleh
,
H. Kita
,
C. Sanderson
,
G. Gleich
Journal of Immunology
1990
Corpus ID: 25515379
We tested the effects of different cytokines on IgA- and IgG-induced eosinophil degranulation in vitro to determine the potential…
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Highly Cited
1989
Highly Cited
1989
Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GMCSF.
E. J. Clutterbuck
,
E. Hirst
,
C. Sanderson
Blood
1989
Corpus ID: 12548031
Recombinant human interleukin-5 (rhIL-5), in either liquid or semi-solid cultures, selectively induced eosinophil production from…
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Highly Cited
1987
Highly Cited
1987
Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5).
H. Campbell
,
W. Tucker
,
+5 authors
I. G. Young
Proceedings of the National Academy of Sciences…
1987
Corpus ID: 34204379
The human eosinophil differentiation factor (EDF) gene was cloned from a genomic library in lambda phage EMBL3A by using a murine…
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Highly Cited
1986
Highly Cited
1986
Murine eosinophil differentiation factor. An eosinophil-specific colony- stimulating factor with activity for human cells
A. Lopez
,
C. Begley
,
D. Williamson
,
D. Warren
,
M. Vadas
,
C. Sanderson
Journal of Experimental Medicine
1986
Corpus ID: 15681728
A purified murine lymphokine, eosinophil differentiation factor (EDF), was found to be a selective stimulus for the clonal…
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Highly Cited
1985
Highly Cited
1985
Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures
C. Sanderson
,
D. Warren
,
M. Strath
Journal of Experimental Medicine
1985
Corpus ID: 11099539
Factors stimulating eosinophil differentiation in vitro have been studied by means of a liquid bone marrow culture system in…
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