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eosinophil activation

The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:add… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Eosinophils are major effector cells in type 2 inflammatory responses and become activated in response to IL-4 and IL-33, yet the… Expand
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Highly Cited
2009
Highly Cited
2009
Peripheral blood and tissue eosinophilia are a prominent feature in allergic diseases and during helminth infections. Eosinophil… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Anti-IL-5 might be a useful therapeutic agent for eosinophilic disorders, yet its immunologic consequences have not… Expand
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Highly Cited
2000
Highly Cited
2000
Although airway inflammation is recognized as a key feature of asthma, the characteristics of airway inflammation in children… Expand
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Highly Cited
1999
Highly Cited
1999
ONO‐1078 (pranlukast) is a leukotriene receptor antagonist developed in Japan. This drug has been shown to be useful in oral… Expand
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Highly Cited
1999
Highly Cited
1999
Eosinophils are the source of various immunoregulatory cytokines, but the membrane molecules involved in their secretion have not… Expand
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Highly Cited
1998
Highly Cited
1998
Interleukin (IL)-5 has been shown to activate many signaling molecules in eosinophils, but their functional relevance remains… Expand
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Highly Cited
1998
Highly Cited
1998
Eosinophils have previously been shown to accumulate around the tissue invasive (L3) stage of sheep gastrointestinal parasites in… Expand
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Highly Cited
1997
Highly Cited
1997
Eosinophils are predominant effector cells not only in allergic diseases but also in connective tissue diseases. The recruitment… Expand
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Highly Cited
1995
Highly Cited
1995
Inflammatory action of the potent chemotaxin C5a has been well characterized on a variety of human cell types, including… Expand
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