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enpiroline

Known as: 4-Pyridinemethanol, alpha-2-piperidinyl-2-(trifluoromethyl)-6-(4-(trifluoromethyl)phenyl)-, (R*,R*)-(+-)-, phosphate (1:1) (salt) 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Pyridines

Narrower (1)

WR 180409

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Disposition of Mefloquine and Enpiroline Is Highly Influenced by a Chronic Schistosoma mansoni Infection
ABSTRACT Chronic Schistosoma mansoni infections lead to severe tissue destruction of the gut wall and liver and can influence… 
Highly Cited
2012
Highly Cited
2012
Antischistosomal Activities of Mefloquine-Related Arylmethanols
ABSTRACT Interesting antischistosomal properties have been documented for the antimalarial mefloquine, a 4-quinolinemethanol. We… 
Highly Cited
1992
Highly Cited
1992
In vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline against Plasmodium falciparum.
The in vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline was compared against chloroquine-resistant… 
1991
1991
In vitro and clinical correlates of mefloquine resistance of Plasmodium falciparum in eastern Thailand.
A series of isolates of Plasmodium falciparum from eastern Thailand was collected prior to and after treatment failure with… 
1989
1989
Crystal and molecular structure of the antimalarial agent enpiroline
To identify common spatial and structural features of amino alcohol antimalarial agents with the eventual goal of designing more… 
1989
1989
Antimalarial drug susceptibility of Plasmodium falciparum isolates from forest fringe dwelling aborigines (Orang Asli) of Peninsular Malaysia.
The drug susceptibility of 70 isolates of Plasmodium falciparum to standard and experimental antimalarials was evaluated using a… 
1988
1988
In vitro activity of pyronaridine against field isolates and reference clones of Plasmodium falciparum.
Pyronaridine, a 9-substituted 1-aza-acridine, was assayed for in vitro activity against clinical and field isolates as well as… 
Review
1988
Review
1988
Evaluation of an in vitro assay system for drug susceptibility of field isolates of Plasmodium falciparum from southern Thailand.
An in vitro assay system has been developed to evaluate the susceptibility of field isolates of Plasmodium falciparum to standard… 
1985
1985
Mefloquine failure in a case of falciparum malaria induced with a multidrug-resistant isolate in a non-immune subject.
In a volunteer with infection induced by injection of the mefloquine-sensitive, multidrug-resistant Vietnam Smith isolate of P… 
1984
1984
Evaluation of the 4-pyridinemethanol WR 180,409 (enpiroline) in the treatment of induced Plasmodium falciparum infections in healthy, non-immune subjects.
WR 180,409 (enpiroline) was administered to 22 non-immune subjects infected with the multi-drug resistant Vietnam Smith isolate… 
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