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enpiroline

Known as: 4-Pyridinemethanol, alpha-2-piperidinyl-2-(trifluoromethyl)-6-(4-(trifluoromethyl)phenyl)-, (R*,R*)-(+-)-, phosphate (1:1) (salt) 
 
National Institutes of Health

Papers overview

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2013
2013
ABSTRACT Chronic Schistosoma mansoni infections lead to severe tissue destruction of the gut wall and liver and can influence… Expand
Highly Cited
2012
Highly Cited
2012
ABSTRACT Interesting antischistosomal properties have been documented for the antimalarial mefloquine, a 4-quinolinemethanol. We… Expand
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Highly Cited
1992
Highly Cited
1992
The in vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline was compared against chloroquine-resistant… Expand
1991
1991
A series of isolates of Plasmodium falciparum from eastern Thailand was collected prior to and after treatment failure with… Expand
1989
1989
To identify common spatial and structural features of amino alcohol antimalarial agents with the eventual goal of designing more… Expand
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1989
1989
The drug susceptibility of 70 isolates of Plasmodium falciparum to standard and experimental antimalarials was evaluated using a… Expand
Review
1989
Review
1989
The most recent acquisitions on chemotherapy and chemoprophylaxis of malaria are reviewed. With regard to chemotherapy, candidate… Expand
1988
1988
Pyronaridine, a 9-substituted 1-aza-acridine, was assayed for in vitro activity against clinical and field isolates as well as… Expand
1985
1985
In a volunteer with infection induced by injection of the mefloquine-sensitive, multidrug-resistant Vietnam Smith isolate of P… Expand
1984
1984
WR 180,409 (enpiroline) was administered to 22 non-immune subjects infected with the multi-drug resistant Vietnam Smith isolate… Expand