enpiroline

Chronic Schistosoma mansoni infections lead to severe tissue destruction of the gut wall and liver and can influence drug… Expand

Interesting antischistosomal properties have been documented for the antimalarial mefloquine, a 4-quinolinemethanol. We evaluated… Expand

The in vitro activity of the enantiomers of mefloquine, halofantrine and enpiroline was compared against chloroquine-resistant… Expand

A series of isolates of Plasmodium falciparum from eastern Thailand was collected prior to and after treatment failure with… Expand

To identify common spatial and structural features of amino alcohol antimalarial agents with the eventual goal of designing more… Expand

The drug susceptibility of 70 isolates of Plasmodium falciparum to standard and experimental antimalarials was evaluated using a… Expand

The most recent acquisitions on chemotherapy and chemoprophylaxis of malaria are reviewed. With regard to chemotherapy, candidate… Expand

Pyronaridine, a 9-substituted 1-aza-acridine, was assayed for in vitro activity against clinical and field isolates as well as… Expand

In a volunteer with infection induced by injection of the mefloquine-sensitive, multidrug-resistant Vietnam Smith isolate of P… Expand

WR 180,409 (enpiroline) was administered to 22 non-immune subjects infected with the multi-drug resistant Vietnam Smith isolate… Expand