enhanceosome

A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0102019952017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Enhancer-binding pluripotency regulators (Sox2 and Oct4) play a seminal role in embryonic stem (ES) cell-specific gene regulation… (More)
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Highly Cited
2009
Highly Cited
2009
Regulatory T (Treg) cells are essential for maintaining immune homeostasis. Although Foxp3 expression marks the commitment of… (More)
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Highly Cited
2007
Highly Cited
2007
Transcriptional activation of the interferon-beta (IFN-beta) gene requires assembly of an enhanceosome containing ATF-2/c-Jun… (More)
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Highly Cited
2007
Highly Cited
2007
Tumor necrosis factor-alpha (TNF-alpha) is a potent mediator of inflammation, inducing expression of a gene network mediated by… (More)
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Highly Cited
2000
Highly Cited
2000
By virtue of its control over major histocompatibility complex class II (MHC-II) gene expression, CIITA represents a key molecule… (More)
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Highly Cited
2000
Highly Cited
2000
Here, we show that the IFN-beta enhanceosome activates transcription by directing the ordered recruitment of chromatin modifying… (More)
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Highly Cited
1998
Highly Cited
1998
Transcriptional activation of the IFN beta gene in response to virus infection requires the assembly of an enhanceosome… (More)
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Highly Cited
1998
Highly Cited
1998
The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We… (More)
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Highly Cited
1997
Highly Cited
1997
A functional interferon-beta gene enhanceosome was assembled in vitro using the purified recombinant transcriptional activator… (More)
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Highly Cited
1995
Highly Cited
1995
We present evidence that transcriptional activation of the human interferon-beta (IFN beta) gene requires the assembly of a… (More)
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