enfuvirtide

Known as: peptide T20, Envelope polyprotein GP160 precursor [Contains: Exterior membrane glycoprotein,GP120, Transmembrane glycoprotein,GP41], enfuvirtide [Chemical/Ingredient] 
A short polypeptide with activity against human immunodeficiency virus (HIV). Enfuvirtide binds to the first heptad-repeat (HR1) in the gp41 viral… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
We study the determinants of vertical integration in a new data set of over 750,000 firms from 93 countries. We present a number… (More)
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Highly Cited
2007
Highly Cited
2007
Enfuvirtide (ENF), the first approved fusion inhibitor (FI) for HIV, is a 36-aa peptide that acts by binding to the heptad repeat… (More)
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Highly Cited
2005
Highly Cited
2005
The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of two… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Persistent infection in resting CD4+ T cells prevents eradication of HIV-1. Since the chromatin remodeling enzyme… (More)
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Review
2004
Review
2004
Fusion inhibitors are a new class of antiretroviral drugs (ARVs) for the treatment of human immunodeficiency virus infection… (More)
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Review
2004
Review
2004
Highly active antiretroviral therapy (HAART) based on combinations of drugs that target key enzymes in the life-cycle of human… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The T-20 vs. Optimized Regimen Only Study 1 (TORO 1) was a randomized, open-label, phase 3 study of enfuvirtide (T-20… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND The T-20 vs. Optimized Regimen Only Study 2 (TORO 2) compared the efficacy and safety of 24 weeks of treatment with… (More)
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Highly Cited
2002
Highly Cited
2002
The synthetic peptide T-20 (enfuvirtide) represents the first of a new class of antiretroviral compounds to demonstrate in vivo… (More)
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Highly Cited
2002
Highly Cited
2002
The upper gastrointestinal tract is a principal route of HIV-1 entry in vertical transmission and after oral–genital contact. The… (More)
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