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eicosanoid metabolism

Known as: arachidonic metabolism, icosanoid metabolism, icosanoid metabolic process 
The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids. [GOC:ma]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2018
051019812018

Related topics

Related topics

2 relations

Broader (2)

fatty acid metabolismhormone metabolism

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
eicosanoid metabolism
fatty acid metabolism
hormone metabolism

Papers overview

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2012
2012
Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease.
OBJECTIVE Preclinical and genetic epidemiologic studies suggest that modulating cytochrome P450 (CYP)-mediated arachidonic acid… (More)
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2011
2011
Activation of the acute inflammatory response alters cytochrome P450 expression and eicosanoid metabolism.
Cytochrome P450 (P450)-mediated metabolism of arachidonic acid regulates inflammation in hepatic and extrahepatic tissue. CYP2C… (More)
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2009
2009
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis.
There is increasing evidence for a major and critical involvement of lipids in signal transduction and cellular trafficking, and… (More)
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2008
2008
Altered eicosanoid metabolism in the cystic fibrosis mouse small intestine.
OBJECTIVES Imbalances in essential fatty acid levels have been reported in cystic fibrosis (CF), which may relate to elevated… (More)
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2005
2005
Redirection of eicosanoid metabolism in mPGES-1-deficient macrophages.
Microsomal prostaglandin E synthase (mPGES)-1 is one of several prostaglandin E synthases involved in prostaglandin H2 (PGH2… (More)
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2002
2002
Lipopolysaccharide-induced leukocyte lipid body formation in vivo: innate immunity elicited intracellular Loci involved in eicosanoid metabolism.
Lipid bodies are rapidly inducible, specialized cytoplasmic domains for eicosanoid-forming enzyme localization, which we… (More)
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1999
1999
Heterogeneity of endothelium-dependent vasodilation in pressurized cerebral and small mesenteric resistance arteries of the rat.
We compared endothelial responses to calcium-mobilizing agents in mesenteric and cerebral resistance arteries of the rat. Middle… (More)
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1997
1997
Modulation of eicosanoid metabolism in endothelial cells in a xenograft model. Role of cyclooxygenase-2.
Lipid inflammatory mediators are thought to play a critical role in the pathogenesis of vascular injury. Among the events which… (More)
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1991
1991
Modification of membrane composition, eicosanoid metabolism, and immunoresponsiveness by dietary omega-3 and omega-6 fatty acid sources, modulators of ultraviolet-carcinogenesis.
Dietary sources of lipids containing predominantly n-3 or n-6 fatty acids (FA) have been examined for effect upon several… (More)
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Highly Cited
1984
Highly Cited
1984
Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs.
The invasion of leukocytes into and around a myocardial infarct was studied in chloralose-anesthetized dogs subjected to 1-hr… (More)
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