efaproxiral

Known as: 2-(4-(((3,5-dimethylanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid, 2-Dacmpp, Efaproxyn 
A synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2014
051020022014

Papers overview

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2008
2008
A safe, functional-group-tolerant and high-throughput version of the trimethylaluminium mediated amide bond formation reaction… (More)
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2007
2007
OBJECTIVE To determine whether efaproxiral, an allosteric modifier of hemoglobin, improves quality of life and quality of… (More)
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2007
2007
Efaproxiral, an allosteric modifier of hemoglobin, reduces hemoglobin-oxygen binding affinity, facilitating oxygen release from… (More)
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2006
2006
PURPOSE To determine whether efaproxiral, an allosteric modifier of hemoglobin, improves survival in patients with brain… (More)
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2006
2006
PURPOSE To determine the prognostic factors for radiographic response and its prognostic value for subsequent survival in… (More)
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2006
2006
Efaproxiral (Efaproxyn™, RSR13), a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity… (More)
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Review
2006
Review
2006
Brain metastases from breast cancer are common and cause significant morbidity and mortality. Treatment with whole-brain… (More)
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2005
2005
PURPOSE Efaproxiral (RSR13) reduces hemoglobin oxygen-binding affinity, facilitates oxygen release, and increases tissue pO2. We… (More)
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2005
2005
PURPOSE To determine quantitatively the changes in oxygenation of intracranial tumors induced by efaproxiral, an allosteric… (More)
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2004
2004
Efaproxiral (RSR13) is a synthetic allosteric modifier of haemoglobin that reduces its oxygen binding affinity. By facilitating… (More)
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