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The optimal management of brain metastases remains controversial. Both whole brain radiotherapy (WBRT) and local treatment… Expand PurposeTo study the efficacy of whole brain radiotherapy (WBRT) with radiosensitizer in comparison with WBRT alone for patients… Expand A safe, functional-group-tolerant and high-throughput version of the trimethylaluminium mediated amide bond formation reaction… Expand Objective:To determine whether efaproxiral, an allosteric modifier of hemoglobin, improves quality of life and quality of… Expand Abstract Hou, H., Khan, N., Grinberg, O. Y., Yu, H., Grinberg, S. A., Lu, S., Demidenko, E., Steffen, R. P. and Swartz, H. M. The… Expand PURPOSE
To determine whether efaproxiral, an allosteric modifier of hemoglobin, improves survival in patients with brain… Expand Opinion statementThe development of brain metastases is often viewed as the end stage of a disease course and engenders… Expand PURPOSE
To determine quantitatively the changes in oxygenation of intracranial tumors induced by efaproxiral, an allosteric… Expand Efaproxiral (RSR13) is a synthetic allosteric modifier of haemoglobin that reduces its oxygen binding affinity. By facilitating… Expand PURPOSE
The objectives of this phase II study were to determine survival, safety, pharmacokinetics (PK), and pharmacodynamics (PD… Expand