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dynorphin A(1-12)

Known as: Dyn A1-12 
 
National Institutes of Health

Papers overview

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2009
2009
Defective Neuropeptide Processing and Ischemic Brain Injury: A Study on Proprotein Convertase 2 and its Substrate Neuropeptide in Ischemic Brains
Using a focal cerebral ischemia model in rats, brain ischemia-induced changes in expression levels of mRNA and protein, and… Expand
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2004
2004
Identification of Stabilized Dynorphin Derivatives for Suppressing Tolerance in Morphine-Dependent Rats
AbstractPurpose. Modulatory actions on morphine-induced effects, such as tolerance and withdrawal, have been noted for dynorphin… Expand
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2000
2000
Dynorphin Stimulates Corticotropin Release from Mouse Anterior Pituitary AtT-20 Cells through Nonopioid Mechanisms
Dynorphin (Dyn) peptides were previously shown to increase plasma corticotropin (ACTH) in the ovine fetus, but the site of its… Expand
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2000
2000
[Effects of high dose of dynorphin on NMDA receptor and NOS activities in spinal cord of rats].
OBJECTIVE To elucidate the effects of N-methyl-D-aspartate(NMDA) receptor and nitric oxide synthase (NOS) activity in dynorphin… Expand
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1996
1996
Interaction between mu and kappa receptors located in the parabrachial area in the opioid control of preference threshold for saccharin: modulatory role of lateral hypothalamic neurones.
In the course of our previous analyses of gustatory reward processes, we showed that, in normal or sham-lesioned rats, the… Expand
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1995
1995
Dynorphin A modulates acute and chronic opioid effects.
A single dose of dynorphin A-(1-13) [dyn A(1-13)] is effective in suppressing the expression of opioid withdrawal and tolerance… Expand
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1991
1991
Decreased glutamate release correlates with elevated dynorphin content in the hippocampus of aged rats with spatial learning deficits.
The effects of aging on extracellular glutamate and tissue dynorphin content in the hippocampus were examined in Fischer-344 rats… Expand
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1991
1991
Effect of opioid peptides on electrically evoked acetylcholine release from Torpedo electromotor neurons
The opioid peptide dynorphin A(1-8) (1 micron) increased acetylcholine release from the Torpedo electric organ by approximately… Expand
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1991
1991
Dynorphins other than dynorphin A(1-17) lack spinal antianalgesic activity but do act on dynorphin A(1-17) receptors.
In recent publications we have proposed that dynorphin (Dyn) A(1-17) functions as an antianalgesic modulator to oppose opioid… Expand
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1990
1990
Competitive and non-competitive NMDA antagonists limit dynorphin A-induced rat hindlimb paralysis
It has been proposed that the endogenous opioid dynorphin A (Dyn A) contributes to the pathogenesis of posttraumatic spinal cord… Expand
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