dynactin complex location

Known as: dynactin complex 
A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1991-2018
051019912018

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Highly Cited
2007
Highly Cited
2007
Sequestration of misfolded proteins into pericentriolar inclusions called aggresomes is a means that cells use to minimize… (More)
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Highly Cited
2003
Highly Cited
2003
Kinesin II is a heterotrimeric plus end-directed microtubule motor responsible for the anterograde movement of organelles in… (More)
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Highly Cited
2000
Highly Cited
2000
NuMA is a large nuclear protein whose relocation to the spindle poles is required for bipolar mitotic spindle assembly. We show… (More)
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Highly Cited
1999
Highly Cited
1999
In axons, organelles move away from (anterograde) and toward (retrograde) the cell body along microtubules. Previous studies have… (More)
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Highly Cited
1998
Highly Cited
1998
The mitotic spindle is often positioned in a characteristic location during development, for example to enable the proper… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND During metazoan development, cell diversity arises primarily from asymmetric cell divisions which are executed in two… (More)
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Highly Cited
1996
Highly Cited
1996
Centractin (Arp1), an actin-related protein, is a component of the dynactin complex. To investigate potential functions of the… (More)
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Highly Cited
1995
Highly Cited
1995
We used affinity chromatography to probe for a direct binding interaction between cytoplasmic dynein and dynactin. Purified… (More)
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Highly Cited
1994
Highly Cited
1994
The dynactin complex visualized by deepetch electron microscopy appears as a short filament 37-nm in length, which resembles F… (More)
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Highly Cited
1991
Highly Cited
1991
Although cytoplasmic dynein is known to attach to microtubules and translocate toward their minus ends, dynein's ability to serve… (More)
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