drug distribution volume

Known as: Volume of Distribution, Vd, Distribution Volume 
The apparent volume occupied by an exogenous compound after it is administered to an organism. This value assumes that the compound is uniformly… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
BACKGROUND Diffuse myocardial fibrosis is a final end point in most cardiac diseases. It is missed by the cardiovascular magnetic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2009
Review
2009
Aging involves progressive impairments in the functional reserve of multiple organs, which might also affect drug metabolism and… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
To use recently developed mechanistic equations to predict tissue-to-plasma water partition coefficients (Kpus), apply these… (More)
  • table I
  • table II
  • table II
  • table III
  • table IV
Is this relevant?
Highly Cited
2005
Highly Cited
2005
CONTENTS Background… (More)
  • table 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
CONTEXT Mutation of the G protein-coupled receptor 54 is associated with a failure of reproductive function. The endogenous… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
UNLABELLED PET studies have been performed using the amyloid binding radiotracer Pittsburgh Compound B (PIB). Previous… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
In drug discovery and nonclinical development the volume of distribution at steady state (V(ss)) of each novel drug candidate is… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
OBJECTIVES We sought to evaluate the association between the extent of coronary artery disease (CAD) and survival in patients… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Many novel experimental therapeutic agents, such as neurotrophic factors, enzymes, biological modifiers, and genetic vectors, do… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
For many compounds (neurotrophic factors, antibodies, growth factors, genetic vectors, enzymes) slow diffusion in the brain… (More)
  • figure 1
  • figure 3
  • figure 4
Is this relevant?