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doxorubicin-HPMA conjugate

Known as: HPMA-doxorubicin, Doxorubicin-HPMA Copolymer Conjugate, Doxorubicin-HPMA 
A copolymer conjugate of the antineoplastic anthracycline doxorubicin and the water-soluble polymer N-(2-hydroxypropyl) methacrylamide (HPMA… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
A well-defined N-(2-hydroxypropyl)methacrylamide-s-N-(3-aminopropyl)methacrylamide (HPMA-s-APMA) copolymer, synthesized via… Expand
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Highly Cited
2009
Highly Cited
2009
Cell specific delivery of small interfering ribonucleic acid (siRNA) using well-defined multivalent folate-conjugated block… Expand
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Highly Cited
2009
Highly Cited
2009
Background There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified… Expand
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Highly Cited
2008
Highly Cited
2008
Synthesis, physicochemical behavior, tumor accumulation and preliminary anticancer activity of a new biodegradable graft… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. Overexpression of hyaluronan (HA) receptors on cancer cells results in enhanced endocytotic uptake of the drug… Expand
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Highly Cited
2004
Highly Cited
2004
A novel class of thermosensitive and biodegradable polymers, poly(N-(2-hydroxypropyl) methacrylamide mono/di lactate) (poly(HPMAm… Expand
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Highly Cited
2001
Highly Cited
2001
N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer conjugates for colon-specific delivery of 9-aminocamptothecin (9-AC) were… Expand
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Highly Cited
1999
Highly Cited
1999
The aim of this study was to compare in vitro and in vivo HPMA copolymer platinates with cisplatin in terms of platinum release… Expand
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Highly Cited
1993
Highly Cited
1993
The aim of this study was to investigate the polymerization contraction and the conversion of light-curing methacrylate resins… Expand
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Highly Cited
1988
Highly Cited
1988
DBA2 mice were inoculated i.p. with 10(5)L1210 cells. Animals subsequently treated with daunomycin (single i.p. dose, 0.25-5.0 mg… Expand
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