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doxorubicin-HPMA conjugate

Known as: HPMA-doxorubicin, Doxorubicin-HPMA Copolymer Conjugate, Doxorubicin-HPMA 
A copolymer conjugate of the antineoplastic anthracycline doxorubicin and the water-soluble polymer N-(2-hydroxypropyl) methacrylamide (HPMA… Expand
National Institutes of Health

Papers overview

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Review
2011
Review
2011
  • A. Bugaj
  • Photochemical & photobiological sciences…
  • 2011
  • Corpus ID: 23973215
Targeted therapy is a new promising therapeutic strategy, created to overcome growing problems of contemporary medicine, such as… Expand
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Highly Cited
2009
Highly Cited
2009
Background There is an immense clinical need for novel therapeutics for the treatment of angiogenesis-dependent calcified… Expand
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Highly Cited
2008
Highly Cited
2008
Synthesis, physicochemical behavior, tumor accumulation and preliminary anticancer activity of a new biodegradable graft… Expand
Highly Cited
2004
Highly Cited
2004
AbstractPurpose. Overexpression of hyaluronan (HA) receptors on cancer cells results in enhanced endocytotic uptake of the drug… Expand
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Highly Cited
2004
Highly Cited
2004
A novel class of thermosensitive and biodegradable polymers, poly(N-(2-hydroxypropyl) methacrylamide mono/di lactate) (poly(HPMAm… Expand
Highly Cited
2004
Highly Cited
2004
AbstractPurpose. We purposed to design a cationic polymer that binds to pDNA to form polyplexes and that subsequently degrades… Expand
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Highly Cited
2001
Highly Cited
2001
N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer conjugates for colon-specific delivery of 9-aminocamptothecin (9-AC) were… Expand
Highly Cited
1999
Highly Cited
1999
The aim of this study was to compare in vitro and in vivo HPMA copolymer platinates with cisplatin in terms of platinum release… Expand
Highly Cited
1993
Highly Cited
1993
The aim of this study was to investigate the polymerization contraction and the conversion of light-curing methacrylate resins… Expand
Highly Cited
1988
Highly Cited
1988
DBA2 mice were inoculated i.p. with 10(5)L1210 cells. Animals subsequently treated with daunomycin (single i.p. dose, 0.25-5.0 mg… Expand
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