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doxorubicin-DNA

Known as: Doxorubicin-DNA Complex, DOX-DNA, Adriamycin-DNA Complex 
A complex comprised of Doxorubicin linked to DNA to enhance the topoisomerase II-mediated interaction with the DNA base pairs and reduce… 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
In this work, we developed a new pH- and temperature-responsive nanochemotherapeutic system based on Doxorubicin (DOX… 
Highly Cited
2012
Highly Cited
2012
Highly Cited
2012
Doxorubicin is a potent anthracycline antibiotic, commonly used to treat a wide range of cancers. Although postulated to… 
2007
2007
PurposeThe importance of understanding the mechanism of action of anticancer agents is sometimes overlooked in the pursuit of new… 
Highly Cited
2006
Highly Cited
2006
Doxorubicin (Adriamycin) is one of the most commonly used chemotherapeutic drugs and exhibits a wide spectrum of activity against… 
2004
2004
The interaction of the antitumour agent doxorubicin with calf thymus DNA is investigated in an aqueous solution at a pH level of… 
2004
2004
SummaryAffinity constants of daunorubicin and doxorubicin for DNA at 37°C and in presence of 10% serum were determined by an… 
1978
1978
The direct and difference spectroscopic methods of determining the binding constant of daunorubicin to DNA were compared. In…