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doxorubicin-DNA

Known as: Doxorubicin-DNA Complex, DOX-DNA, Adriamycin-DNA Complex 
A complex comprised of Doxorubicin linked to DNA to enhance the topoisomerase II-mediated interaction with the DNA base pairs and reduce… Expand
National Institutes of Health

Papers overview

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2012
2012
The cytotoxicity of doxorubicin, a clinically used anti-neoplastic drug, can be enhanced by formaldehyde (either endogenous or… Expand
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2012
2012
Doxorubicin is a potent anthracycline antibiotic, commonly used to treat a wide range of cancers. Although postulated to… Expand
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2010
2010
Doxorubicin is an anthracycline anticancer agent that functions primarily by inhibiting topoisomerase II, but also forms covalent… Expand
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Review
2010
Review
2010
Barminomycin is a member of the anthracycline class of anticancer agents and was originally discovered as a pink/red complex with… Expand
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2007
2007
PurposeThe importance of understanding the mechanism of action of anticancer agents is sometimes overlooked in the pursuit of new… Expand
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Highly Cited
2006
Highly Cited
2006
Doxorubicin (Adriamycin) is one of the most commonly used chemotherapeutic drugs and exhibits a wide spectrum of activity against… Expand
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2004
2004
SummaryAffinity constants of daunorubicin and doxorubicin for DNA at 37°C and in presence of 10% serum were determined by an… Expand
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2004
2004
The interaction of the antitumour agent doxorubicin with calf thymus DNA is investigated in an aqueous solution at a pH level of… Expand
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1979
1979
SummaryWe have compared the toxicologic, pharmacologic, and therapeutic properties of the DNA complexes of daunorubicin and… Expand
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1974
1974
Abstract The complex formed between adriamycin and DNA possesses the physicochemical and in vitro biological characteristics of a… Expand
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