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doxorubicin-DNA

Known as: Doxorubicin-DNA Complex, DOX-DNA, Adriamycin-DNA Complex 
A complex comprised of Doxorubicin linked to DNA to enhance the topoisomerase II-mediated interaction with the DNA base pairs and reduce… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
In this work, we developed a new pH- and temperature-responsive nanochemotherapeutic system based on Doxorubicin (DOX… Expand
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Highly Cited
2012
Highly Cited
2012
The cytotoxicity of doxorubicin, a clinically used anti-neoplastic drug, can be enhanced by formaldehyde (either endogenous or… Expand
Highly Cited
2012
Highly Cited
2012
Doxorubicin is a potent anthracycline antibiotic, commonly used to treat a wide range of cancers. Although postulated to… Expand
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2010
2010
Doxorubicin is an anthracycline anticancer agent that functions primarily by inhibiting topoisomerase II, but also forms covalent… Expand
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Review
2010
Review
2010
Barminomycin is a member of the anthracycline class of anticancer agents and was originally discovered as a pink/red complex with… Expand
2007
2007
PurposeThe importance of understanding the mechanism of action of anticancer agents is sometimes overlooked in the pursuit of new… Expand
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Highly Cited
2006
Highly Cited
2006
Doxorubicin (Adriamycin) is one of the most commonly used chemotherapeutic drugs and exhibits a wide spectrum of activity against… Expand
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2004
2004
The interaction of the antitumour agent doxorubicin with calf thymus DNA is investigated in an aqueous solution at a pH level of… Expand
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1978
1978
The direct and difference spectroscopic methods of determining the binding constant of daunorubicin to DNA were compared. In… Expand
Highly Cited
1974
Highly Cited
1974
Abstract The complex formed between adriamycin and DNA possesses the physicochemical and in vitro biological characteristics of a… Expand