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dolichyl-phosphate beta-D-mannosyltransferase activity

Known as: dolichol-phosphate mannose synthase activity, GDPmannose:dolichyl-phosphate mannosyltransferase activity, dolichyl mannosyl phosphate synthase activity 
Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate. [EC:2.4.1.83]
National Institutes of Health

Papers overview

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2003
2003
A deficiency in dolichyl-P-glucose:Glc1Man9GlcNAc2-PP-dolichyl alpha3-glucosyltransferase defines a new subtype of congenital disorders of glycosylation.
The underlying causes of type I congenital disorders of glycosylation (CDG I) have been shown to be mutations in genes encoding… Expand
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2002
2002
Deficiency of dolichyl-P-Man:Man7GlcNAc2-PP-dolichyl mannosyltransferase causes congenital disorder of glycosylation type Ig.
Deficiency of the endoplasmic reticulum enzyme dolichyl-phosphate mannose (Dol-P-Man):Man(7)GlcNAc(2)-PP-dolichyl… Expand
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1999
1999
Carbohydrate deficient glycoprotein syndrome type IV: deficiency of dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase.
Type IV of the carbohydrate deficient glycoprotein syndromes (CDGS) is characterized by microcephaly, severe epilepsy, minimal… Expand
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1999
1999
Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana.
The cell surface of the parasitic protozoan Leishmania mexicana is coated by glycosylphosphatidylinositol (GPI)-anchored… Expand
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1996
1996
Substrate specificity of the dolichol phosphate mannose: glucosaminyl phosphatidylinositol alpha1-4-mannosyltransferase of the glycosylphosphatidylinositol biosynthetic pathway of African…
The biosynthesis of glycosylphosphatidylinositol (GPI) precursors in Trypanosoma brucei involves the D-mannosylation of D-GlcN… Expand
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1991
1991
Protein O-glycosylation in Saccharomyces cerevisiae. Purification and characterization of the dolichyl-phosphate-D-mannose-protein O-D-mannosyltransferase.
The enzyme dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase has been solubilized from Saccharomyces cerevisiae… Expand
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1989
1989
Amphomycin inhibits mannosylphosphoryldolichol synthesis by forming a complex with dolichylmonophosphate.
The inhibitory effect of the lipopeptide antibiotic amphomycin on the mechanism of mannosylphosphoryldolichol biosynthesis by… Expand
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1987
1987
cAMP-mediated protein phosphorylation of microsomal membranes increases mannosylphosphodolichol synthase activity.
We have investigated the possible role of a cAMP-mediated protein-phosphorylation event(s) as the key regulatory mechanism in… Expand
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1985
1985
Stimulation by dolichol phosphate-mannose and phospholipids of the biosynthesis of N-acetylglucosaminylpyrophosphoryl dolichol.
Dolichol phosphate-mannose (dol-P-mannose) has been shown previously to stimulate the reaction: dolichol phosphate + UDP-[3H… Expand
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1985
1985
Activation of dolichyl-phospho-mannose synthase by phospholipids.
Dolichyl-phospho-mannose synthase, or GDPmannose:dolichyl-phosphate mannosyltransferase (EC 2.4.1.83), was solubilized from rat… Expand
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