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ditercalinium
Known as:
2,2'-((4,4'-Bipiperidine)-1,1'-Diyldiethylene)Bis(10-Methoxy-7H-Pyrido(4,3-c)Carbazolium)
Â
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1984-2012
0
2
4
6
8
1984
2012
Related topics
Related topics
6 relations
Broader (3)
Antineoplastic Agents
Carbazoles
Intercalating Agents
Narrower (2)
NSC 335153
NSC 366241
ditercalinium chloride
Related mentions per year
Related mentions per year
1947-2018
1940
1960
1980
2000
2020
ditercalinium
Antineoplastic Agents
Intercalating Agents
Carbazoles
NSC 335153
NSC 366241
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Ditercalinium chloride, a pro-anticancer drug, intimately associates with mammalian mitochondrial DNA and inhibits its replication
Mayumi Okamaoto
,
T. Ohsato
,
+5 authors
Dongchon Kang
Current Genetics
2003
Ditercalinium chloride was originally synthesized for use as an anticancer drug and was then found to deplete mitochondrial DNA…Â
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2002
2002
Tight binding of the antitumor drug ditercalinium to quadruplex DNA.
Carolina Carrasco
,
Frédéric Rosu
,
+8 authors
Christian Bailly
Chembiochem : a European journal of chemical…
2002
The structural selectivity of the DNA-binding antitumor drug ditercalinium was investigated by competition dialysis with a series…Â
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2002
2002
DNA sequence recognition by the antitumor drug ditercalinium.
Stephen D G Crow
,
Christian Bailly
,
Christiane Garbay-Jaureguiberry
,
Bernard Pierre Roques
,
B. Shaw
,
Michael J. Waring
Biochemistry
2002
The antitumor drug ditercalinium is a rare example of a noncovalent DNA-binding ligand that forms bisintercalation complexes via…Â
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2002
2002
Structural perturbations in DNA caused by bis-intercalation of ditercalinium visualised by atomic force microscopy
Torunn Berge
,
Nigel S. Jenkins
,
Richard B. Hopkirk
,
Michael J. Waring
,
J. Michael Edwardson
,
Robert M. Henderson
Nucleic Acids Research
2002
Atomic force microscopy (AFM) has been used to examine perturbations in the tertiary structure of DNA induced by the binding of…Â
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1992
1992
DNA-ditercalinium interactions: implications for recognition of damaged DNA.
Loren Dean Williams
,
Qiang Gao
Biochemistry
1992
Ditercalinium is unique among known DNA-binding chemotherapeutic agents. Ditercalinium treatment of Escherichia coli causes cell…Â
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1991
1991
Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.
Qiang Gao
,
Loren Dean Williams
,
+4 authors
Ashleigh Rich
Proceedings of the National Academy of Sciences…
1991
Ditercalinium is a synthetic anticancer drug that binds to DNA by bis-intercalation and activates DNA repair processes. In…Â
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1990
1990
DNase I susceptibility of bent DNA and its alteration by ditercalinium and distamycin.
R. Mendoza
,
Judit E Markovits
,
Jean - Pierre Jaffrezou
,
Gaëlle Muzard
,
Jean-Bernard Le Pecq
Biochemistry
1990
The bending of kinetoplast DNA from Crithidia fasciculata is thought to be related to the periodic distribution of AA or TT…Â
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1990
1990
Selective alteration of mitochondrial function by Ditercalinium (NSC 335153), a DNA bisintercalating agent.
Caroline Esnault
,
S. C. Brown
,
+4 authors
Jean-Bernard Le Pecq
Biochemical pharmacology
1990
The bifunctional intercalator Ditercalinium (NSC 335153) demonstrates an anti-tumoral cytotoxicity markedly different from other…Â
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1988
1988
Cytoplasmic accumulation of ditercalinium in rat hepatocytes and induction of mitochondrial damage.
R Fellous
,
Dominique Coulaud
,
+4 authors
Alain J. Gouyette
Cancer research
1988
Ditercalinium (NSC 335153), a 7H-pyridocarbazole dimer, is a bis-intercalating agent whose mechanism of action differs from that…Â
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1986
1986
Effects of the bifunctional antitumor intercalator ditercalinium on DNA in mouse leukemia L1210 cells and DNA topoisomerase II.
Judit E Markovits
,
Yves Pommier
,
+4 authors
Karsten Kohn
Cancer research
1986
Ditercalinium, a 7H-pyridocarbazole dimer (bisintercalator) belongs to a new class of antineoplastic intercalating agents. To…Â
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