ditercalinium

Known as: 2,2'-((4,4'-Bipiperidine)-1,1'-Diyldiethylene)Bis(10-Methoxy-7H-Pyrido(4,3-c)Carbazolium) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2012
0246819842012

Papers overview

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2003
2003
Ditercalinium chloride was originally synthesized for use as an anticancer drug and was then found to deplete mitochondrial DNA… (More)
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2002
2002
The structural selectivity of the DNA-binding antitumor drug ditercalinium was investigated by competition dialysis with a series… (More)
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2002
2002
The antitumor drug ditercalinium is a rare example of a noncovalent DNA-binding ligand that forms bisintercalation complexes via… (More)
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2002
2002
Atomic force microscopy (AFM) has been used to examine perturbations in the tertiary structure of DNA induced by the binding of… (More)
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1992
1992
Ditercalinium is unique among known DNA-binding chemotherapeutic agents. Ditercalinium treatment of Escherichia coli causes cell… (More)
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1991
1991
Ditercalinium is a synthetic anticancer drug that binds to DNA by bis-intercalation and activates DNA repair processes. In… (More)
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1990
1990
The bending of kinetoplast DNA from Crithidia fasciculata is thought to be related to the periodic distribution of AA or TT… (More)
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1990
1990
The bifunctional intercalator Ditercalinium (NSC 335153) demonstrates an anti-tumoral cytotoxicity markedly different from other… (More)
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1988
1988
Ditercalinium (NSC 335153), a 7H-pyridocarbazole dimer, is a bis-intercalating agent whose mechanism of action differs from that… (More)
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1986
1986
Ditercalinium, a 7H-pyridocarbazole dimer (bisintercalator) belongs to a new class of antineoplastic intercalating agents. To… (More)
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