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ditercalinium
Known as:
2,2'-((4,4'-Bipiperidine)-1,1'-Diyldiethylene)Bis(10-Methoxy-7H-Pyrido(4,3-c)Carbazolium)
National Institutes of Health
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Related topics
Related topics
6 relations
Broader (3)
Antineoplastic Agents
Carbazoles
Intercalating Agents
Narrower (3)
NSC 335153
NSC 366241
ditercalinium chloride
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Natural product DNA major groove binders.
Paris L. Hamilton
,
D. Arya
Natural product reports (Print)
2012
Corpus ID: 205794120
Covering: 1980 to 2011. Major groove recognition of DNA by proteins utilizes the variation in hydrogen bond donor/acceptor…
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Highly Cited
2002
Highly Cited
2002
Tight Binding of the Antitumor Drug Ditercalinium to Quadruplex DNA
C. Carrasco
,
F. Rosu
,
+8 authors
C. Bailly
ChemBioChem
2002
Corpus ID: 5915303
The structural selectivity of the DNA‐binding antitumor drug ditercalinium was investigated by competition dialysis with a series…
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Highly Cited
2002
Highly Cited
2002
Structural perturbations in DNA caused by bis-intercalation of ditercalinium visualised by atomic force microscopy
T. Berge
,
Nigel S. Jenkins
,
Richard B. Hopkirk
,
M. Waring
,
J. Edwardson
,
R. Henderson
Nucleic Acids Res.
2002
Corpus ID: 3080118
Atomic force microscopy (AFM) has been used to examine perturbations in the tertiary structure of DNA induced by the binding of…
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2002
2002
Synthesis, cytotoxic activities and proposed mode of binding of a series of bis([(9-oxo-9,10-dihydroacridine-4-carbonyl)amino]alkyl) alkylamines.
M. Braña
,
Luis Casarrubios
,
+5 authors
B. de Pascual-Teresa
European journal of medicinal chemistry
2002
Corpus ID: 36491635
1997
1997
Isolation and characterization of mitochondrial DNA-less lines from various mammalian cell lines by application of an anticancer drug, ditercalinium.
K. Inoue
,
D. Takai
,
+6 authors
J. Hayashi
Biochemical and Biophysical Research…
1997
Corpus ID: 22781815
Since ethidium bromide was not effective in mouse cell lines for isolating mitochondrial DNA (mtDNA)-less cells (rho zero cells…
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Highly Cited
1993
Highly Cited
1993
Inhibitors of human immunodeficiency virus integrase.
M. Fesen
,
K. Kohn
,
F. Leteurtre
,
Y. Pommier
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 33637500
In an effort to further extend the number of targets for development of antiretroviral agents, we have used an in vitro integrase…
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Highly Cited
1991
Highly Cited
1991
Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex.
Q. Gao
,
L. Williams
,
+4 authors
A. Rich
Proceedings of the National Academy of Sciences…
1991
Corpus ID: 13140385
Ditercalinium is a synthetic anticancer drug that binds to DNA by bis-intercalation and activates DNA repair processes. In…
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1989
1989
1H and 31P nuclear magnetic resonance studies of the differences in DNA deformation induced by anti-tumoral 7H-pyrido[4,3-c]carbazole dimers.
M. Delepierre
,
R. Maroun
,
C. Garbay‐Jaureguiberry
,
J. Igolen
,
B. Roques
Journal of Molecular Biology
1989
Corpus ID: 24258294
1988
1988
Selective loss of mitochondrial DNA after treatment of cells with ditercalinium (NSC 335153), an antitumor bis-intercalating agent.
E. Ségal-Bendirdjian
,
D. Coulaud
,
B. Roques
,
J. Le Pecq
Cancer Research
1988
Corpus ID: 8117352
Ditercalinium (NSC 335153), a bifunctional intercalating molecule with antitumor activity, is found to express its toxicity…
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1986
1986
Effects of the bifunctional antitumor intercalator ditercalinium on DNA in mouse leukemia L1210 cells and DNA topoisomerase II.
J. Markovits
,
Y. Pommier
,
+4 authors
K. Kohn
Cancer Research
1986
Corpus ID: 24161979
Ditercalinium, a 7H-pyridocarbazole dimer (bisintercalator) belongs to a new class of antineoplastic intercalating agents. To…
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