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disprocynium 24

Known as: 1,1'-diisopropyl-2,4'-cyanine, disprocynium24 
National Institutes of Health

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Quinolines

Papers overview

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2010
2010
Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human alpha 1- and alpha 2-adrenoceptor subtypes.
2002
2002
Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells
The extraneuronal monoamine transporter from rat (EMTr) was heterologously expressed by stable transfection in human embryonic… 
1998
1998
Eukaliuric natriuresis and diuresis in response to disprocynium24: studies on the tubular site of action
We previously described that 1,1’-diisopropyl-2,4’-cyanine (disprocynium24, DP24) exerts an eukaliuric diuresis and natriuresis… 
1997
1997
Disprocynium24 induces a dopamine-independent, eukaliuric diuresis and natriuresis in the anaesthetized rat
In the anaesthetized rat, intravenous administration of the isocyanine 1,1′-diisopropyl-2,4′-cyanine (disprocynium24) at doses up… 
1996
1996
Disprocynium24, a novel inhibitor of the extraneuronal monoamine transporter, has potent effects on the inactivation of circulating noradrenaline and adrenaline in conscious rat
The role of extraneuronal uptake in terminating the actions of catecholamines has been difficult to evaluate in vivo, largely… 
1996
1996
Pharmacokinetic and α1-adrenoceptor antagonistic properties of two cyanine-type inhibitors of extraneuronal monoamine transport
Abstract1,1′-Diethyl-2,2′-cyanine (decynium22) and 1,1′-diisopropyl-2,4′-cyanine (disprocynium24) are highly potent inhibitors of… 
1996
1996
The role of extraneuronal amine transport systems for the removal of extracellular catecholamines in the rabbit
As selective inhibitors of the extraneuronal monoamine uptake system (uptake2) suitable for in-vivo studies were not available… 
1993
1993
Cyanine-related compounds: a novel class of potent inhibitors of extraneuronal noradrenaline transport
SummaryThe neurotransmitter noradrenaline is removed from the extracellular space by neuronal and extraneuronal transport… 
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