disobutamide

Known as: alpha-(2-bis(1-methylethyl)amino)-alpha-(2-chlorophenyl)-1-piperidinebutanamide 
 

Topic mentions per year

Topic mentions per year

1980-1993
0119801993

Papers overview

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1993
1993
1. The importance of pharmacokinetics and physicochemical data in the discovery and development of a new mono-cationic… (More)
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1991
1991
In the investigation of cellular changes associated with intracellular drug storage, we incubated cultured rabbit aorta muscle… (More)
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1990
1990
Cultured cells were found to be highly useful for investigating intracellular storage of amphiphilic compounds using disobutamide… (More)
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1989
1989
Disobutamide, a bis tertiary amine (pKa1 = 8.6; pKa2 = 10.2) cationic amphiphilic compound, and a putative cardiac antiarrhythmic… (More)
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1989
1989
In the investigation of the dynamic nature of intracellular drug-induced storage disorder associated with clear cytoplasmic… (More)
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1988
1988
Analogues of the dibasic antiarrhythmic agent disobutamide (2) were prepared and evaluated for antiarrhythmic efficacy… (More)
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1986
1986
A subchronic oral toxicity study of disobutamide, a piperidine ring compound with antiarrhythmic activity, was conducted at doses… (More)
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1985
1985
Cellular uptake of disobutamide (D), and clear cytoplasmic vacuoles (CCV) induction by D in cultured rat urinary bladder… (More)
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1984
1984
Smooth muscle cells released by protease from the coronary artery of dogs were cultured in M199 supplemented with 10% fetal calf… (More)
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1981
1981
The effects of disopyramide (DP) and a new antiarrhythmic agent, disobutamide (DB) on cardiac conduction were studied using His… (More)
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