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disobutamide

Known as: alpha-(2-bis(1-methylethyl)amino)-alpha-(2-chlorophenyl)-1-piperidinebutanamide 
 
National Institutes of Health

Papers overview

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1991
1991
In the investigation of cellular changes associated with intracellular drug storage, we incubated cultured rabbit aorta muscle… Expand
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1990
1990
Cultured cells were found to be highly useful for investigating intracellular storage of amphiphilic compounds using disobutamide… Expand
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1989
1989
Disobutamide, a bis tertiary amine (pKa1 = 8.6; pKa2 = 10.2) cationic amphiphilic compound, and a putative cardiac antiarrhythmic… Expand
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1989
1989
In the investigation of the dynamic nature of intracellular drug-induced storage disorder associated with clear cytoplasmic… Expand
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1987
1987
Abstract Disobutamide (D), an antiarrhythmic cationic amphiphilic amine (CAA), was withdrawn from clinical testing when clear… Expand
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1986
1986
A subchronic oral toxicity study of disobutamide, a piperidine ring compound with antiarrhythmic activity, was conducted at doses… Expand
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1986
1986
When cultured rat urinary bladder carcinoma cells are incubated with medium containing disobutamide (D), they take up D… Expand
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1985
1985
Abstract Cellular uptake of disobutamide (D), and clear cytoplasmic vacuoles (CCV) induction by D in cultured rat urinary bladder… Expand
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1984
1984
Smooth muscle cells released by protease from the coronary artery of dogs were cultured in M199 supplemented with 10% fetal calf… Expand
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1980
1980
The synthesis and biological evaluation of a series of alpha, alpha-bis[(dialkylamino)alkyl]phenylacetamides, 2, are presented… Expand
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