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National Institutes of Health
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Disila-galaxolide and derivatives: synthesis and olfactory characterization of silicon-containing derivatives of the musk odorant galaxolide.
Jennifer B. Bauer
Corpus ID: 7357467
A series of silicon-containing derivatives of the polycyclic musk odorant galaxolide (4 a) was synthesized, that is, disila…
Silicon Analogues of the RXR‐Selective Retinoid Agonist SR11237 (BMS649): Chemistry and Biology
Corpus ID: 3127434
C/Si switch: Twofold sila‐substitution (C/Si exchange) in the RXR‐selective retinoids 4 a (SR11237) and 5 a leads to 4 b (disila…
Synthesis and Pharmacological Characterization of Disila‐AM80 (Disila‐tamibarotene) and Disila‐AM580, Silicon Analogues of the RARα‐Selective Retinoid Agonists AM80 (Tamibarotene) and AM580
Corpus ID: 10426303
Retinoic acid receptors, which act as heterodimers between either one of three RARs (RARa, b, g) and RXRs (RXRa, b, g), are…
Odorant Design Based on the Carbon/Silicon Switch Strategy
Chemistry & biodiversity
Corpus ID: 32167842
Silicon chemistry has been demonstrated to be a novel source of chemical diversity in odorant design. The carbon/silicon switch…
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