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dihydropteroate synthase activity

Known as: dihydropteroate synthetase activity, DHPS activity, dihydropteroate diphosphorylase activity 
Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate. [EC… Expand
National Institutes of Health

Papers overview

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2007
2007
The enzymes 6-hydroxymethylpterin pyrophosphokinase (HPPK) and dihydropteroate synthase (DHPS) catalyze sequential steps in… Expand
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Review
1998
Review
1998
  • Walter T. Hughes
  • Clinical infectious diseases : an official…
  • 1998
  • Corpus ID: 11510500
Dapsone, with or without trimethoprim or pyrimethamine, has strong anti-Pneumocystis carinii activity, as demonstrated by in… Expand
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1980
1980
Publisher Summary This chapter discusses the cell-free dihydropteroate synthetase (DHPS) activity. DHPS catalyzes the formation… Expand
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1977
1977
Dihydrofolate synthetase activity is widely distributed in various microorganisms and mushrooms. Animals and microorganisms i.e… Expand
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1976
1976
Abstract Aerobacter aerogenes mutant 62-1 AC requires high concentrations of 4-aminobenzoate for growth. The mutant accumulates N… Expand
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1974
1974
Extracts from Neisseria meningitidis and N. gonorrhoeae with varying susceptibility to sulfanilamide have been investigated for… Expand
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1973
1973
The inhibitory action of various diphenylsulfones and sulfonamides on dihydropteroate synthetase partially purified from… Expand
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1973
1973
Abstract A method is described for the determination of the enzymic synthesis of 7,8-dihydropteroic acid in a cell-free system of… Expand
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