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dichloro(phenanthroline)gold(III)

Known as: (Au(phen)Cl2)Cl, Auphen 
National Institutes of Health

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1 relation

Broader (1)

Organogold Compounds

Papers overview

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2020
2020
Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3
2019
2019
Endodontic applications of the metallo-drug, Auphen.
............................................................................................................ ii Acknowledgements… 
2018
2018
Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection
Within the liver a single Plasmodium parasite transforms into thousands of blood-infective forms to cause malaria. Here, we use… 
2018
2018
Selective targeting of PARP-1 zinc finger recognition domains with Au(iii) organometallics.
The binding of Au(iii) complexes to the zinc finger domain of the anticancer drug target PARP-1 was studied using a hyphenated… 
2016
2016
Auphen and dibutyryl cAMP suppress growth of hepatocellular carcinoma by regulating expression of aquaporins 3 and 9 in vivo.
AIM To investigate whether the regulation of aquaporin 3 (AQP3) and AQP9 induced by Auphen and dibutyryl cAMP (dbcAMP) inhibits… 
2016
2016
Differential regulation of the expression of aquaporins 3 and 9 by Auphen and dbcAMP in the SMMC-7721 hepatocellular carcinoma cell line
Aquaglycero-aquaporins (agAQPs) are the structural foundation of rapid water transport and they appear to participate in cancer… 
Highly Cited
2014
Highly Cited
2014
Functional Inhibition of Aquaporin‐3 With a Gold‐Based Compound Induces Blockage of Cell Proliferation
AQP3 has been correlated with higher transport of glycerol, increment of ATP content, and larger proliferation capacity. Recently… 
2014
2014
A Gold Coordination Compound as a Chemical Probe to Unravel Aquaporin‐7 Function
Aquaporins (AQPs) are membrane water/glycerol channels that are involved in many physiological functions. Aquaporin‐based… 
Highly Cited
2012
Highly Cited
2012
Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound
Aquaporins (AQPs) are membrane channels that conduct water and small solutes such as glycerol and are involved in many… 
2012
2012
The gold-based compound Auphen affects proliferation rate of AQP3 expressing cells
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