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diazoxon

Known as: O,O-diethyl O-(2-isopropyl-4-methylpyrimid-6-yl)phosphate, diazinon-oxon 
 
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Human paraoxonase 1 (PON1) has broad substrate specificity and has been shown to protect against exposure to some… Expand
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2007
2007
Pesticide detoxification is a central feature of selective toxicity and safety evaluation. Two of the principal enzymes involved… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND In the developing brain, serotonin (5HT) systems are among the most sensitive to disruption by organophosphates… Expand
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Highly Cited
2006
Highly Cited
2006
The objective was to determine PON1 status as a predictor for organophosphorus insecticide sensitivity in a cohort of Latina… Expand
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Highly Cited
2005
Highly Cited
2005
HDL-associated paraoxonase type 1 (PON1) can protect LDL and HDL against oxidative modification in vitro and therefore may… Expand
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2004
2004
The cytochrome P450 (CYP)-mediated biotransformation of the organophosphorothioate insecticides chlorpyrifos and diazinon was… Expand
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2004
2004
The authors examined the relation between 50 widely used agricultural pesticides and lung cancer incidence in the Agricultural… Expand
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Highly Cited
2000
Highly Cited
2000
Human paraoxonase (PON1) is a polymorphic, high-density lipoprotein (HDL)-associated esterase that hydrolyzes the toxic… Expand
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Review
1999
Review
1999
In human populations, serum paraoxonase (PON1) exhibits a substrate dependent polymorphism. The Arg192 isoform hydrolyzes… Expand
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Highly Cited
1996
Highly Cited
1996
Many organophosphorus compounds (OPs) are potent cholinesterase inhibitors, accounting for their use as insecticides and… Expand
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