Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

diazonamide A

National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Heterocyclic Compounds, 4 or More RingsOxazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Total synthesis of diazonamide A.
A total synthesis of the marine natural product diazonamide A (1) has been accomplished. This work features a highly… 
  • table 1
  • table 1
  • table 3
  • table 4
  • table 5
Highly Cited
2010
Highly Cited
2010
A concise formal synthesis of diazonamide A by the stereoselective construction of the C10 quaternary center.
Diazonamide A (1, Figure 1) is a marine-derived natural product with potent antimitotic activity and an unusual architecture.[1… 
Review
2008
Review
2008
The synthetic challenge of diazonamide A, a macrocyclic indole bis-oxazole marine natural product.
The complex structure of the marine metabolic diazonamide A comprises a dichlorinated indole bis-oxazole heteroaromatic fragment… 
Highly Cited
2007
Highly Cited
2007
An expedient formal total synthesis of (-)-diazonamide A via a powerful, stereoselective O-aryl to C-aryl migration to form the C10 quaternary center.
During the course of studies on the synthesis of diazonamide A 1, an unusual O-aryl into C-aryl rearrangement was discovered that… 
Highly Cited
2004
Highly Cited
2004
Chemistry and biology of diazonamide A: second total synthesis and biological investigations.
As an especially unique target for chemical synthesis, diazonamide A has the potential to be constructed through a plethora of… 
  • table 1
  • table 3
  • table 2
Highly Cited
2004
Highly Cited
2004
Chemistry and biology of diazonamide A: first total synthesis and confirmation of the true structure.
With the addition of a tenth ring, the exchange of an oxygen atom for a nitrogen in the heart of the molecule, and a different… 
  • figure 1
  • table 2
  • table 1
  • table 3
Highly Cited
2004
Highly Cited
2004
Studies toward diazonamide A: initial synthetic forays directed toward the originally proposed structure.
A brief introduction into the chemistry of diazonamide A (1) is followed by first-generation sequences to access the originally… 
Highly Cited
2003
Highly Cited
2003
Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
The marine ascidian Diazona angulata was the source organism for the complex cytotoxic peptide diazonamide A. The molecular… 
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Highly Cited
2000
Highly Cited
2000
Synthesis of C(3) benzofuran-derived bisaryl quaternary centers: approaches to diazonamide A.
[reaction: see text] Two complementary strategies for the synthesis of the diazonamide A bisaryl quaternary center are described… 
  • figure 1
2000
2000
Progress toward synthesis of diazonamide A. Preparation of a 3-(oxazol-5-yl)-4-trifluoromethyl-sulfonyloxyindole and its use in biaryl coupling reactions.
[formula: see text] The synthesis of a 3-oxazol-5-yl-indole-4-triflate is described, featuring a Schölkopf reaction to prepare… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE