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diacetoxyscirpenol

Known as: Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 4,15-diacetate, (3.alpha.,4.beta.)- (9CI), Trichothec-9-ene-3,4, 15-triol, 12,13-epoxy-, 4,15-diacetate, (3.alpha.,4.beta.)- (9CI), 3.Alpha,4.Beta, 15-triol, 12, 13-epoxy-,4, 15-diacetate (8CI) 
A trichothecene mycotoxin and potent teratogen. Anguidine inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating… 
National Institutes of Health

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5 relations

Broader (4)

Antineoplastic AgentsMycotoxinsSesquiterpenesTrichothecenes

Narrower (1)

NSC 141537

Papers overview

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2005
2005
Effects of Diacetoxyscirpenol and Fusaric Acid on Poults: Individual and Combined Effects of Dietary Diacetoxyscirpenol and Fusaric Acid on Turkey Poult Performance
Turkey poults were randomly placed in batteries and fed one of four dietary treatments: control (C); control plus 4ppm… 
2000
2000
A Letter to the Parent(s) of a Child with Developmental Apraxia of Speech. Part IV: Treatment of DAS.
1986
1986
Improved method for production of antibodies against T-2 toxin and diacetoxyscirpenol in rabbits
A new, improved approach for the production of antibodies against T-2 toxin and diacetoxyscirpenol (DAS) was developed. The… 
1984
1984
Anguidine: a broad phase II study of the Southeastern Cancer Study Group.
Anguidine, a phase II agent, was used to treat 276 patients with solid tumors. The overall evaluability rate was 68%. Hematologic… 
1983
1983
Selective protection by anguidine of normal versus transformed cells against 1-beta-D-arabinofuranosylcytosine and Adriamycin.
Anguidine, a protein synthesis inhibitor, has been shown previously to induce a reversible arrest of cell progression through all… 
1982
1982
Structural modifications of anguidin and antitumor activities of its analogues.
Approximately 60 derivatives of anguidin were prepared for evaluation of antitumor activities. Positions 3, 4, 8-10, and 15 were… 
1982
1982
Phase II study of anguidine in gastrointestinal malignancies: a Southwest Oncology Group study.
The Southwest Oncology Group conducted a phase II study of anguidine in 134 patients with gastrointestinal malignancies… 
1981
1981
Reduction of 1-beta-D-arabinofuranosylcytosine and adriamycin cytotoxicity following cell cycle arrest by anguidine.
The protein synthesis inhibitor anguidine induced a frozen cell cycle state in exponentially growing Chinese hamster ovary cells… 
1979
1979
Phase II study of anguidine in advanced breast cancer.
A phase II evaluation of anguidine was carried out in 30 patients with advanced refractory breast cancer. A dose of 5.0 mg/m2… 
1975
1975
Comparative studies on microbial and chemical modifications of trichothecene mycotoxins.
The microbial modification of several trichothecene mycotoxins by trichothecene-producing strains of Fusarium nivale and F…