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dexchlorpheniramine

Known as: dexchlorpheniramine [Chemical/Ingredient], D-Chlorpheniramine, gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine 
An alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine competitively blocks H1 receptors, thereby… 
National Institutes of Health

Related topics

Related topics

10 relations
Angle Closure GlaucomaChlo-AmineDrug AllergyHistamine H1 Receptor Antagonists [MoA]

Broader (2)

ChlorpheniramineHistamine H1 Antagonists

Narrower (2)

Dexchlorpheniramine maleatePolaronil

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors.
2004
2004
Retentivity and enantioselectivity of uniformly sized molecularly imprinted polymers for d-chlorpheniramine and -brompheniramine in hydro-organic mobile phases.
2002
2002
The effects of a sedative antihistamine, d‐chlorpheniramine, on visuomotor spatial discrimination and regional brain activity as measured by positron emission tomography (PET)
Although most people taking antihistamines have experienced sedation and impaired performance, the neural correlates of these… 
2002
2002
Histamine regulation of interleukin-18-initiating cytokine cascade is associated with down-regulation of intercellular adhesion molecule-1 expression in human peripheral blood mononuclear cells.
In the previous study, we demonstrated that interleukin (IL)-18 up-regulated intercellular adhesion molecule-1 (ICAM-1… 
2002
2002
Possible involvement of tachykinin NK(1) and NMDA receptors in histamine-induced hyperalgesia in mice.
2001
2001
Determination of active ingredients in cough-cold preparations by micellar liquid chromatography.
2001
2001
Anaphylaxis due to Hypersensitivity to Anisakis simplex
Anaphylactic reactions are among the most frequent causes for requests for emergency medical care. It is possible that no clear… 
1985
1985
Histamine H1-receptors in the guinea-pig urinary bladder.
1977
1977
Effects of 5HT uptake inhibitors on the pressor response to 5HT in the pithed rat. The significance of the 5HT blocking property.
1976
1976
Effect of the antihistaminic agents meclastine and dexchlorpheniramine on the response of human growth hormone to arginine infusion and insulin hypoglycemia.
Histamine is found in most tissues including the central nervous system. Here it reaches the highest concentrations in the… 
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