dexchlorpheniramine

Known as: dexchlorpheniramine [Chemical/Ingredient], D-Chlorpheniramine, gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine 
An alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine competitively blocks H1 receptors, thereby… (More)
National Institutes of Health

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2008
2008
Previous research has demonstrated that a high dose of histamine (1600 pmol) injected i.t. in mice can evoke nociceptive… (More)
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2005
2005
Orexins are neuropeptides that are mostly expressed in the posterior and lateral hypothalamus, and related to the central control… (More)
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2004
2004
INTRODUCTION Dexchlorpheniramine (DH) is a classical or first generation antihistamine belonging to the ethanolamine group… (More)
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2004
2004
BACKGROUND Mequitazine is a so-called 'non-sedative' second-generation antihistamine even though it has never been firmly… (More)
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2002
2002
We previously reported that histamine H(1) receptor gene knockout mice (H1KO) showed lower spontaneous nociceptive threshold to… (More)
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2000
2000
Antihistamine induced cognitive decline was evaluated using positron emission tomography (PET) measurement of histamine H1… (More)
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2000
2000
We produced ovalbumin (OVA)-sensitized rats as an animal model of nasal allergy. Intranasal instillation of OVA induced… (More)
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1999
1999
In the present study we analyzed the effect of continuous intraventricular infusion of the histamine H1 receptor antagonist d… (More)
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1987
1987
First-generation H1-antagonist antihistamines such as hydroxyzine have a significant ability to cross the blood-brain barrier and… (More)
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1970
1970
Mice were given L-DOPA i.p. in doses ranging from 7.8 to 500 mg/kg with and without previous administration of MK 485, a compound… (More)
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