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desthiobiotin

Known as: 5-methyl-2-oxo-4-imidazolidinehexanoic acid, dethiobiotin 
 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The crystal structure of biotin synthase from Escherichia coli in complex with S-adenosyl-L-methionine and dethiobiotin has been… Expand
Highly Cited
2004
Highly Cited
2004
Biotin synthase (BioB) converts dethiobiotin into biotin by inserting a sulfur atom between C6 and C9 of dethiobiotin in an S… Expand
Highly Cited
2002
Highly Cited
2002
The high-affinity binding of biotin to avidin, streptavidin, and related proteins has been exploited for decades. However, a… Expand
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Review
2001
Review
2001
The genetics and mechanistic enzymology of biotin biosynthesis have been the subject of much investigation in the last decade… Expand
Highly Cited
2001
Highly Cited
2001
Biotin synthase is an iron-sulfur protein that utilizes AdoMet to catalyze the presumed radical-mediated insertion of a sulfur… Expand
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Review
1999
Review
1999
The thiamin and biotin biosynthetic pathways utilize elaborate strategies for the transfer of sulfur from cysteine to cofactor… Expand
Highly Cited
1997
Highly Cited
1997
The Strep-tag, an artificial peptide ligand of streptavidin, has gained use as an affinity handle for the purification and… Expand
Highly Cited
1995
Highly Cited
1995
We have developed a radiochemical method for the measurement of biotin synthase activity in vitro. A cell-free extract from an… Expand
Highly Cited
1994
Highly Cited
1994
The adhesion force between the tip of an atomic force microscope cantilever derivatized with avidin and agarose beads… Expand
Highly Cited
1994
Highly Cited
1994
We report here the first purification of the protein encoded by the Escherichia coli bioB gene. One species of this protein runs… Expand