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desosamine

National Institutes of Health

Papers overview

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2012
2012
Structural factors behind erm macrolide resistance were studied through synthesis of new macrolide derivates possessing truncated… 
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2009
2009
D-desosamine (1) is a 3-(N,N-dimethylamino)-3,4,6-trideoxyhexose found in a number of macrolide antibiotics including methymycin… 
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2009
2009
The cytochrome P-450 PikC from Streptomyces venezuelae exhibits significant substrate tolerance and performs multiple… 
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Highly Cited
2005
Highly Cited
2005
ABSTRACT An Escherichia coli strain capable of producing the potent antibiotic erythromycin C (Ery C) was developed by expressing… 
2005
2005
Analysis of the tylosin gene cluster in Streptomyces fradiae uncovered an ORF, tyl1a, homologous to a hexose 3,4-isomerase found… 
2002
2002
Methylation catalyzed by an S-adenosylmethionine- (AdoMet-) dependent methyltransferase is an effective means to alter the… 
Highly Cited
2001
Highly Cited
2001
BACKGROUND Combinatorial biosynthesis techniques using polyketide synthases (PKSs) in heterologous host organisms have enabled… 
Highly Cited
1999
Highly Cited
1999
[formula: see text] The appended sugars in macrolide antibiotics are indispensable to the biological activities of these… 
Review
1998
Review
1998
In a survey of microbial systems capable of generating unusual metabolite structural variability, Streptomyces venezuelae ATCC… 
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Highly Cited
1997
Highly Cited
1997
Abstract The gene cluster (ery) governing the biosynthesis of the macrolide antibiotic erythromycin A by Saccharopolyspora… 
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