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desmethylselegiline

Known as: demethyl-deprenyl-DMD, di-N-propargylamphetamine, N-desmethyl-selegiline 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

AmphetaminesMonoamine Oxidase Inhibitors

Narrower (1)

desmethylselegiline, (-)-isomer

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Differential effects of selegiline on glucose synthesis in rabbit kidney-cortex tubules and hepatocytes. In vitro and in vivo studies.
2003
2003
Detection, quantification, metabolism, and behavioral effects of selegiline in horses.
Selegiline ([R]-[-]N,alpha-dimethyl-N-2- propynylphenethylamine or l-deprenyl), an irreversible inhibitor of monoamine oxidase… 
2001
2001
Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole
Abstract. Objective: To characterise the effects of itraconazole, a potent inhibitor of CYP3A4, on the pharmacokinetics of… 
2001
2001
Cytochrome P450 isoform-specific in vitro methods to predict drug metabolism and interactions
Cytochromes P450 (P450, CYP) are a superfamily of enzymes that participate especially in the oxidative metabolism of various… 
2001
2001
CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline
Abstract. Objectives: To address the relevance of cytochrome P-450 (CYP) 2C19 polymorphism for the pharmacokinetics and dynamics… 
2000
2000
Determination of enantiomeric metabolites of l-deprenyl, d-methamphetamine, and racemic methamphetamine in urine by capillary electrophoresis: comparison of deprenyl use and methamphetamine use.
The enantiomeric analysis of urine collected from rats administered l-deprenyl, d-methamphetamine (MA), or dl-MA and from healthy… 
1999
1999
Biotransformation of deprenyl enantiomers
SummaryRats were treated with either (−)- or (+)-deprenyl, and the metabolites extracted from the plasma, liver, kidney and heart… 
1998
1998
CYP2D6 polymorphism is not crucial for the disposition of selegiline
1996
1996
Absorption and Presystemic Metabolism of Selegiline Hydrochloride at Different Regions in the Gastrointestinal Tract in Healthy Males
AbstractPurpose. The absorption and disposition of selegiline (SEL) and its metabolites N-desmethylselegiline (DMS), L… 
1996
1996
Bioavailability of two selegiline hydrochloride tablet products.
The bioavailability of two selegiline HCl (CAS 14611-52-0) tablet products was compared in a single-blind, single-dose… 
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