desmethylcyproheptadine

To investigate the pharmacokinetics of cyproheptadine (CPH) and its metabolites, the plasma concentration and urinary excretion… (More)

The relationship between age-related differences in cyproheptadine (CPH)-induced alteration of endocrine pancreas function and… (More)

Pretreatment with an oral dose (45 mg/kg) of cyproheptadine (CPH), a drug that inhibits secretion and synthesis of insulin. 3 hr… (More)

The contribution of drug metabolites to cyproheptadine (CPH)-induced alterations in endocrine pancreatic β-cells was investigated… (More)

The effects of pretreatment with inhibitors of drug metabolism on the biotransformation of cyproheptadine (CPH) and the ability… (More)

The tissue distribution of unchanged drug and metabolites in pregnant rats was studied following oral administration of… (More)

The susceptibility of fetal endocrine pancreas to the diabetogenic action of cyproheptadine was investigated. Cyproheptadine (5… (More)

The role of a direct effect of serotonin (5-HT) on PRL secretion at the pituitary level is uncertain. The present study… (More)

Cyproheptadine and its metabolite desmethylcyproheptadine were shown to suppress directly the release of adrenocorticotrophin… (More)

The effects of cyproheptadine, desmethylcyproheptadine, serotonin, gamma-amino-butyric acid (GABA) and sodium valproate were… (More)