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desmethylcyproheptadine
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1983-1993
0
1
2
1983
1993
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Cyproheptadine
Related mentions per year
Related mentions per year
1960-2018
1960
1980
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2020
desmethylcyproheptadine
Cyproheptadine
Papers overview
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1993
1993
Pharmacokinetics of cyproheptadine and its metabolites in rats.
Masahiro Iwaki
,
Tadashi Ogiso
,
Yukihiko Fujii
,
Tadatoshi Tanino
,
Yukako Ito
,
Y. Miki
Biological & pharmaceutical bulletin
1993
To investigate the pharmacokinetics of cyproheptadine (CPH) and its metabolites, the plasma concentration and urinary excretion…Â
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1991
1991
Postnatal changes in the insulin-depleting action and disposition of cyproheptadine in rats.
Seinen Chow
,
L. J. Fischer
Developmental pharmacology and therapeutics
1991
The relationship between age-related differences in cyproheptadine (CPH)-induced alteration of endocrine pancreas function and…Â
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1991
1991
Interactions of diabetogenic compounds: cyproheptadine and alloxan.
Anjan Chatterjee
,
V Varayotha
,
L. J. Fischer
Fundamental and applied toxicology : official…
1991
Pretreatment with an oral dose (45 mg/kg) of cyproheptadine (CPH), a drug that inhibits secretion and synthesis of insulin. 3 hr…Â
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1989
1989
Cyproheptadine metabolites inhibit proinsulin and insulin biosynthesis and insulin release in isolated rat pancreatic islets
Samson A. Chow
,
Josie L. Falany
,
Lawrence J. Fischer
Cell Biology and Toxicology
1989
The contribution of drug metabolites to cyproheptadine (CPH)-induced alterations in endocrine pancreatic β-cells was investigated…Â
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1988
1988
Evidence that drug metabolites are involved in cyproheptadine-induced loss of pancreatic insulin.
Seinen Chow
,
Douglas E. Rickert
,
L. J. Fischer
The Journal of pharmacology and experimental…
1988
The effects of pretreatment with inhibitors of drug metabolism on the biotransformation of cyproheptadine (CPH) and the ability…Â
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1987
1987
Metabolism and disposition of cyproheptadine and desmethylcyproheptadine in pregnant and fetal rats.
Seinen Chow
,
L. J. Fischer
Drug metabolism and disposition: the biological…
1987
The tissue distribution of unchanged drug and metabolites in pregnant rats was studied following oral administration of…Â
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1986
1986
Susceptibility of fetal rat endocrine pancreas to the diabetogenic action of cyproheptadine.
Seinen Chow
,
L. J. Fischer
Toxicology and applied pharmacology
1986
The susceptibility of fetal endocrine pancreas to the diabetogenic action of cyproheptadine was investigated. Cyproheptadine (5…Â
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1985
1985
The mechanism of action of cyproheptadine on prolactin release by cultured anterior pituitary cells.
Steven W. J. Lamberts
,
Theo Verleun
,
R. v. Oosterom
Life sciences
1985
The role of a direct effect of serotonin (5-HT) on PRL secretion at the pituitary level is uncertain. The present study…Â
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1983
1983
Cyproheptadine and desmethylcyproheptadine directly inhibit the release of adrenocorticotrophin and beta-lipotrophin/beta-endorphin activity from the neurointermediate lobe of the rat pituitary gland…
Steven W. J. Lamberts
,
Eva Bons
,
Piet Uitterlinden
,
W. H. L. Hackeng
The Journal of endocrinology
1983
Cyproheptadine and its metabolite desmethylcyproheptadine were shown to suppress directly the release of adrenocorticotrophin…Â
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1983
1983
Effect of cyproheptadine, desmethylcyproheptadine, gamma-amino-butyric acid and sodium valproate on adrenocorticotrophin secretion by cultured pituitary tumour cells from three patients with Nelson's…
Steven W. J. Lamberts
,
Theo Verleun
,
Eva Bons
,
Piet Uitterlinden
,
R. v. Oosterom
The Journal of endocrinology
1983
The effects of cyproheptadine, desmethylcyproheptadine, serotonin, gamma-amino-butyric acid (GABA) and sodium valproate were…Â
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