desmethylcyproheptadine

To investigate the pharmacokinetics of cyproheptadine (CPH) and its metabolites, the plasma concentration and urinary excretion… Expand

The relationship between age-related differences in cyproheptadine (CPH)-induced alteration of endocrine pancreas function and… Expand

The contribution of drug metabolites to cyproheptadine (CPH)-induced alterations in endocrine pancreatic β-cells was investigated… Expand

The effects of pretreatment with inhibitors of drug metabolism on the biotransformation of cyproheptadine (CPH) and the ability… Expand

The tissue distribution of unchanged drug and metabolites in pregnant rats was studied following oral administration of… Expand

The susceptibility of fetal endocrine pancreas to the diabetogenic action of cyproheptadine was investigated. Cyproheptadine (5… Expand

The role of a direct effect of serotonin (5-HT) on PRL secretion at the pituitary level is uncertain. The present study… Expand

The effects of cyproheptadine, desmethylcyproheptadine, serotonin, gamma-amino-butyric acid (GABA) and sodium valproate were… Expand

Cyproheptadine and its metabolite desmethylcyproheptadine were shown to suppress directly the release of adrenocorticotrophin… Expand

Desmethylcyproheptadine-10,11-epoxide, cyproheptadine-10,11-epoxide, and desmethylcyproheptadine were identified in rat urine… Expand