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Pharmacokinetic drug-drug interactions often occur at the level of P-glycoprotein (Pgp). To study possible interactions caused by… Expand A chiral capillary electrophoresis (CE) system allowing simultaneous enantiomer determination of citalopram (CIT) and its… Expand Although citalopram has gained wide acceptance in the treatment of depression and anxiety disorders, its use during pregnancy and… Expand A newly developed disposable device for liquid-phase microextraction (LPME) was evaluated for the capillary electrophoresis (CE… Expand The in vitro biotransformation of bupropion to hydroxybupropion was studied in human liver microsomes and microsomes containing… Expand The selective serotonin reuptake inhibitors (SSRIs) comprise citalopram, fluoxetine, fluvoxamine, paroxetine, and sertraline and… Expand BACKGROUND
Biotransformation of citalopram (CT), a newly available selective serotonin reuptake inhibitor antidepressant, to its… Expand A case is presented with measurements of the selective serotonin reuptake inhibitor (SSRI)-antidepressant citalopram in serum of… Expand The relationship between the metabolism of the selective serotonin reuptake inhibitor citalopram and the sparteine and… Expand 1. The aromatic 2-hydroxylation of imipramine was studied in microsomes from three human livers. The kinetics were best described… Expand