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desethyloxybutynin

Known as: Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(ethylamino)-2-butynyl ester, N-desethyloxybutynin, deethyloxybutynin 
 
National Institutes of Health

Papers overview

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2009
2009
  • C. Chapple
  • Nature Reviews Urology
  • 2009
  • Corpus ID: 1825420
Antimuscarinic drugs are the first-line treatment for overactive bladder. However, traditional formulations are associated with a… Expand
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2008
2008
An enantioselective method using liquid-phase microextraction (LPME) followed by HPLC analysis was developed for the… Expand
2007
2007
In vitro studies and the multiple applications of an oxybutynin (OXY) transdermal delivery system to Japanese healthy volunteers… Expand
Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To characterize the enantiomers of oxybutynin (OXY) and N-desethyloxybutynin (DEO) following transdermal and… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. The purpose of this work was to characterize in vitro/in vivo delivery and pharmacokinetics of oxybutynin (OXY… Expand
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2003
2003
  • Hohyun Kim, S. Han
  • Journal of pharmaceutical and biomedical analysis
  • 2003
  • Corpus ID: 25686407
A sensitive and selective liquid chromatographic method coupled with tandem mass spectrometry (LC-MS/MS) was developed for the… Expand
2002
2002
Plasma protein binding of N-desethyloxybytynin (DEOXY), a major active metabolite of oxybutynin (OXY), was investigated… Expand
2002
2002
OBJECTIVES To establish an in vivo model to screen new muscarinic antagonists for the treatment of overactive urinary bladder and… Expand
Highly Cited
2001
Highly Cited
2001
UNLABELLED Aims : Dry mouth is a common side-effect seen with immediate-release oxybutynin (IR-Oxy). Ditropan XL [(Oxy-XL), a… Expand
1981
1981
Oxybutynin is rapidly metabolized in rat liver microsomes. Two major primary oxidation products were identified as N-desethyl… Expand