desethyloxybutynin

Antimuscarinic drugs are the first-line treatment for overactive bladder. However, traditional formulations are associated with a… Expand

Oxybutynin chloride has been effectively used for treating overactive bladder syndrome for more than three decades. The evolution… Expand

An enantioselective method using liquid-phase microextraction (LPME) followed by HPLC analysis was developed for the… Expand

In vitro studies and the multiple applications of an oxybutynin (OXY) transdermal delivery system to Japanese healthy volunteers… Expand

AbstractPurpose. To characterize the enantiomers of oxybutynin (OXY) and N-desethyloxybutynin (DEO) following transdermal and… Expand

AbstractPurpose. The purpose of this work was to characterize in vitro/in vivo delivery and pharmacokinetics of oxybutynin (OXY… Expand

A sensitive and selective liquid chromatographic method coupled with tandem mass spectrometry (LC-MS/MS) was developed for the… Expand

Plasma protein binding of N-desethyloxybytynin (DEOXY), a major active metabolite of oxybutynin (OXY), was investigated… Expand

UNLABELLED Aims : Dry mouth is a common side-effect seen with immediate-release oxybutynin (IR-Oxy). Ditropan XL [(Oxy-XL), a… Expand

Oxybutynin is rapidly metabolized in rat liver microsomes. Two major primary oxidation products were identified as N-desethyl… Expand