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desethyloxybutynin

Known as: Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(ethylamino)-2-butynyl ester, N-desethyloxybutynin, deethyloxybutynin 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Mandelic Acids

Narrower (1)

desethyloxybutynin hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Transdermal Oxybutynin
Abstract▴ Oxybutynin inhibits contraction of the detrusor muscle in the overactive bladder by binding to muscarinic M3 receptors… 
2009
2009
Urinary Incontinence: Oxybutynin topical gel for overactive bladder
  • C. Chapple
  • Nature Reviews Urology
  • 2009
  • Corpus ID: 1825420
Antimuscarinic drugs are the first-line treatment for overactive bladder. However, traditional formulations are associated with a… 
2009
2009
The evolution of transdermal therapy for overactive bladder
  • P. Sand
  • Current urology reports
  • 2009
  • Corpus ID: 27615958
Oxybutynin chloride has been effectively used for treating overactive bladder syndrome for more than three decades. The evolution… 
2007
2007
Stereoselective pharmacokinetics of oxybutynin and N-desethyloxybutynin in vitro and in vivo
In vitro studies and the multiple applications of an oxybutynin (OXY) transdermal delivery system to Japanese healthy volunteers… 
Highly Cited
2004
Highly Cited
2004
Pharmacokinetics of the R- and S-Enantiomers of Oxybutynin and N-Desethyloxybutynin Following Oral and Transdermal Administration of the Racemate in Healthy Volunteers
AbstractPurpose. To characterize the enantiomers of oxybutynin (OXY) and N-desethyloxybutynin (DEO) following transdermal and… 
Highly Cited
2004
Highly Cited
2004
Pharmacokinetics and Metabolism of Transdermal Oxybutynin: In Vitro and in Vivo Performance of a Novel Delivery System
AbstractPurpose. The purpose of this work was to characterize in vitro/in vivo delivery and pharmacokinetics of oxybutynin (OXY… 
2002
2002
Effect of muscarinic antagonists on micturition pressure measured by cystometry in normal, conscious rats.
2002
2002
Binding study of desethyloxybutynin using high-performance frontal analysis method.
Highly Cited
2001
Highly Cited
2001
Effect of OROS controlled-release delivery on the pharmacokinetics and pharmacodynamics of oxybutynin chloride.
UNLABELLED Aims : Dry mouth is a common side-effect seen with immediate-release oxybutynin (IR-Oxy). Ditropan XL [(Oxy-XL), a… 
1981
1981
Metabolism of Oxybutynin: establishment of desethyloxybutynin and oxybutynin N-oxide formation in rat liver preparation using deuterium substitution and gas chromatographic mass spectrometric…
Oxybutynin is rapidly metabolized in rat liver microsomes. Two major primary oxidation products were identified as N-desethyl… 
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