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desethylamodiaquine
Known as:
4-((7-chloro-4-quinolinyl)amino)-2-((ethylamino)methyl)phenol
, monodesethylamodiaquine
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Amodiaquine
N-desethylamodiaquine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Population pharmacokinetic modelling and simulation of antimalaria drugs to optimize dosing in neglected populations
A. Ali
2017
Corpus ID: 203833287
Malaria is a mosquito-borne infectious disease which affects humans and other animals. In 2016 the World Health Organization (WHO…
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2013
2013
Plasmodium falciparum with Multidrug Resistance 1 Gene Duplications, Senegal
Aurélie Pascual
,
B. Fall
,
+8 authors
B. Pradines
Emerging Infectious Diseases
2013
Corpus ID: 7269925
To the Editor: Amplification and overexpression of the Plasmodium falciparum multidrug resistance 1 gene (Pfmdr1) have been…
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2013
2013
in Benin Artemisinin-Based Combination Therapies Susceptibility and Clinical Effectiveness of Drug Ex Vivo Associated with Plasmodium falciparum Polymorphisms
S. Dahlström
,
A. Aubouy
,
+9 authors
Sandrine Houzéb
2013
Corpus ID: 115864763
Published Ahead of Print 7 October 2013. 10.1128/AAC.01790-12. 2014, 58(1):1. DOI: Antimicrob. Agents Chemother. Deloron, Jacques…
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2013
2013
The Metabolism of Antiparasitic Drugs and Pharmacogenetics in African Populations: From Molecular Mechanisms to Clinical Applications
C. Masimirembwa
2013
Corpus ID: 36135440
We characterised over 20 antiparasitic drugs with respect to the enzymes responsible for their metabolism. We showed that CYP2C8…
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2012
2012
In-Vitro Susceptibility of Plasmodium falciparum to Antimalarial Drugs in Abuja, Nigeria
I. Peletiri
,
B. Matur
,
N. Ibecheozor
,
J. Ihongbe
,
T. Wakama
2012
Corpus ID: 73602602
The susceptibility of Plasmodium falciparum to Chloroquine, Quinine, Dihydroartemisinin and Monodesethylamodiaquine was…
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2011
2011
Effects of Food on the Pharmacokinetics of Amodiaquine in Healthy Volunteers
S. J. Olugbenga
,
O. Olugbenga
,
A. A. Akande
2011
Corpus ID: 78449493
Amodiaquine (AQ) is a 4-aminoquinoline derivative which is intrinsically more active than the other 4- aminoquinoline…
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2002
2002
IN VZTRO ACTIVITY OF DIHYDROARTEMISININ AGAINST CLINICAL , ISOLATES OF PLASMODZUM FALCZPARUM IN YAOUNDE , CAMEROON AND
K. Basco
2002
Corpus ID: 8590153
The in vitro activities of dihydroartemkinin (the biologically active metabolite of artemisinin derivatives), chloroquine…
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Review
1986
Review
1986
[Pharmacokinetics of antimalarials: quinine and mefloquine, halofantrine, qinghaosu, amino-4-quinolines].
F. Verdier
,
E. Pussard
,
M. Blayo
Medecine tropicale : revue du Corps de sante…
1986
Corpus ID: 38941035
The development of new sensitive and specific assays (HPLC) have enabled the pharmacokinetics of antimalarial drugs to be studied…
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1985
1985
Failure to detect amodiaquine in the blood after oral administration.
L. Salako
,
O. R. Idowu
British Journal of Clinical Pharmacology
1985
Corpus ID: 24902031
Plasma and red blood cell concentrations of amodiaquine (AM) and its metabolite, desethylamodiaquine (DAM), were monitored at…
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1985
1985
[Pharmacokinetics of amodiaquine and prevention of Plasmodium falciparum malaria].
E. Pussard
,
F. Verdier
,
F. Faurisson
,
M. Blayo
Bulletin de la Societe de pathologie exotique et…
1985
Corpus ID: 44838407
Amodiaquine might appear as an alternative in prophylaxis of chloroquine-resistant P. falciparum malaria. In an attempt to…
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