desethylamodiaquine

Known as: 4-((7-chloro-4-quinolinyl)amino)-2-((ethylamino)methyl)phenol, monodesethylamodiaquine 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2016
051019852016

Papers overview

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2011
2011
In order to study the pharmacokinetic properties of amodiaquine and desethylamodiaquine during pregnancy, 24 pregnant women in… (More)
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2010
2010
The control of malaria is challenged by resistance of Plasmodium falciparum to multiple drugs. New combination regimens are now… (More)
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Highly Cited
2009
Highly Cited
2009
Chloroquine (CQ) resistance (CQR) in Plasmodium falciparum originated from at least six foci in South America, Asia, and Oceania… (More)
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2007
2007
The potential role of polymorphisms in the pfcrt and pfmdr1 genes and in vitro susceptibility to amodiaquine and… (More)
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2007
2007
The study aimed to characterize the population pharmacokinetics of amodiaquine (AQ) and its major metabolite N… (More)
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2006
2006
Plasmodium falciparum in-vitro susceptibility to chloroquine (CQ), monodesethylamodiaquine, quinine and dihydroartemisinin was… (More)
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2006
2006
We determined the level of in vitro resistance of Plasmodium falciparum parasites to standard antimalarial drugs, such as… (More)
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Highly Cited
2002
Highly Cited
2002
Amodiaquine (AQ) metabolism to N-desethylamodiaquine (DEAQ) is the principal route of disposition in humans. Using human liver… (More)
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1996
1996
The in vitro activity of nine antimalarials was determined against 119 fresh clinical isolates of Plasmodium falciparum obtained… (More)
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1989
1989
The antimalarial activities of amodiaquine, the desethyl metabolite of amodiaquine, chloroquine, and mefloquine were evaluated… (More)
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