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desethylamodiaquine

Known as: 4-((7-chloro-4-quinolinyl)amino)-2-((ethylamino)methyl)phenol, monodesethylamodiaquine 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The control of malaria is challenged by resistance of Plasmodium falciparum to multiple drugs. New combination regimens are now… Expand
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Highly Cited
2009
Highly Cited
2009
Chloroquine (CQ) resistance (CQR) in Plasmodium falciparum originated from at least six foci in South America, Asia, and Oceania… Expand
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2007
2007
A total of 248 Plasmodium falciparum isolates were sampled in travelers with malaria who came to Marseille, France from Comoros… Expand
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2006
2006
We determined the level of in vitro resistance of Plasmodium falciparum parasites to standard antimalarial drugs, such as… Expand
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2006
2006
Plasmodium falciparum in-vitro susceptibility to chloroquine (CQ), monodesethylamodiaquine, quinine and dihydroartemisinin was… Expand
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Highly Cited
2006
Highly Cited
2006
The choice of partner drug is critical for artemisinine-based combination therapy (ACT) to remain effective and amodiaquine (AQ… Expand
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Highly Cited
2002
Highly Cited
2002
Amodiaquine (AQ) metabolism to N-desethylamodiaquine (DEAQ) is the principal route of disposition in humans. Using human liver… Expand
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1999
1999
The short-term in vitro growth of Plasmodium falciparum parasites in the asexual erythrocytic stage and the in vitro activities… Expand
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Highly Cited
1996
Highly Cited
1996
The in vitro activity of nine antimalarials was determined against 119 fresh clinical isolates of Plasmodium falciparum obtained… Expand
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Review
1996
Review
1996
SummaryMalaria is associated with a reduction in the systemic clearance and apparent volume of distribution of the cinchona… Expand
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