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desethylamiodarone

Known as: Methanone, (2-butyl-3-benzofuranyl)(4-(2-(ethylamino)ethoxy)-3,5-diiodophenyl)-, N-desethylamiodarone, deethylamiodarone 
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
Amiodarone is an increasingly popular and uniquely effective antiarrhythmic agent for which population pharmacokinetic parameters… Expand
Highly Cited
1996
Highly Cited
1996
Effective electrokinetic field-amplified sample injection occurring at the capillary inlet from a sample volume equivalent… Expand
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Review
1992
Review
1992
Amiodarone, originally developed over 20 years ago, is a potent antiarrhythmic drug with the actions of all antiarrhythmic drug… Expand
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Highly Cited
1990
Highly Cited
1990
Amiodarone has been shown to produce microvesicular steatosis of the liver in some recipients. We have determined the effects of… Expand
1990
1990
To investigate the relationship between the amount of amiodarone and the major metabolite N-desethylamiodarone found in the lung… Expand
Highly Cited
1990
Highly Cited
1990
The incidence and clinical predictors of amiodarone pulmonary toxicity were examined in 573 patients treated with amiodarone for… Expand
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Highly Cited
1989
Highly Cited
1989
Since recent in vivo evidence suggests that the benzofuran antiarrhythmic drug amiodarone has a direct toxic effect on the human… Expand
Highly Cited
1987
Highly Cited
1987
The distribution of the antiarrhythmic drug amiodarone and its principal lipophilic metabolite, desethylamiodarone, was… Expand
Highly Cited
1987
Highly Cited
1987
It has been suggested that some of the effects of long-term amiodarone therapy may be due to accumulation of a metabolite… Expand
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Highly Cited
1986
Highly Cited
1986
Summary: The electrophysiologic (EP) effects of chronically administered amiodarone (AM) is known, but the nature of its acute… Expand