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desciclovir

Known as: 2-((2-Amino-9H-purin-9-yl)methoxy)ethanol, 6-deoxyacyclovir, Ethanol, 2-((2-amino-9H-purin-9-yl)methoxy)- 
A prodrug of acyclovir with activity against viruses in the herpesvirus family. Desciclovir is absorbed from the gastrointestinal tract and is… Expand
National Institutes of Health

Papers overview

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2004
2004
SummaryA515U (6-deoxyacyclovir) is an analogue of acyclovir devoid of antiviral activity in vitro but which is well absorbed and… Expand
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1991
1991
The mechanism of transport of desciclovir (DCV)--a structural analogue and prodrug of acyclovir (ACV) which provides an improved… Expand
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Highly Cited
1990
Highly Cited
1990
The efficacy of desciclovir, an analog of acyclovir, in eliminating lesions of oral hairy leukoplakia (HL) and suppressing… Expand
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Highly Cited
1989
Highly Cited
1989
The limited oral absorption in rodents of the antiherpesvirus agent 9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine (BRL 39123… Expand
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Highly Cited
1988
Highly Cited
1988
The mechanism of transport of the antiviral agent acyclovir (ACV) into human erythrocytes has been investigated. Initial… Expand
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1987
1987
Because of the incomplete absorption of acyclovir (ACV) when given orally in humans, efforts have been made to develop a prodrug… Expand
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1987
1987
The antiviral drug, acyclovir, has been used in the treatment of chronic type B hepatitis. High serum concentrations of acyclovir… Expand
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1987
1987
D.c. polarography of 2-amino-6-chloropurine in aqueous medium over a broad pH range revealed two diffusion waves, the first of… Expand
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1986
1986
BW A515U (6-Deoxyacyclovir) is a pro-drug of acyclovir and almost 100% is absorbed orally. 250 mg orally 6-hourly for 10 days was… Expand
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Highly Cited
1984
Highly Cited
1984
Acyclovir [9-[(2-hydroxyethoxy)methyl]guanine] is an acyclic guanine nucleoside analogue that is widely used clinically as an… Expand
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