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desacetyl-alacepril

Known as: L-Phenylalanine, N-(1-(3-mercapto-2-methyl-1-oxopropyl)-L-prolyl)-, (S)-, deacetylalacepril, desacetylalacepril 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Captopril

Narrower (1)

DU 1227
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Sialic Acid 9-O-Acetylesterase Catalyzes the Hydrolyzing Reaction from Alacepril to Deacetylalacepril
AbstractPurpose. In this work, the alacepril thiolesterase, which catalyzes the hydrolyzing reaction of the thiolester linkage in… 
1994
1994
Poster abstractDesacetylalacepril, a metabolite of alacepril, prevents oxidation of LDL and inhibits cholesteryl ester accumulation in mouse peritoneal macrophages
1989
1989
Antihypertensive mechanism of alacepril. Effects of its metabolites on the peripheral sympathetic nervous system.
To elucidate the antihypertensive mechanisms of alacepril (DU-1219), the drug itself and its metabolites, desacetylalacepril (DU… 
1986
1986
General pharmacology of the novel angiotensin converting enzyme inhibitor alacepril. 2nd communication: Effects on central nervous and sensory systems and on the other functions.
The effects of 1-[(S)-3-acetylthio-2-methylpropanoyl]-L-prolyl-L-phenylalanine (alacepril, DU-1219), an orally active angiotensin… 
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