deriglidole

 
National Institutes of Health

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ImidazolesIndoles

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1998
1998
Effects of acute alpha 2-blockade on insulin action and secretion in humans.
We tested whether acute alpha 2-blockade affects insulin secretion, glucose and fat metabolism, thermogenesis, and hemodynamics… (More)
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1998
1998
Mechanisms of the hypoglycemic effects of the alpha2-adrenoceptor antagonists SL84.0418 and deriglidole.
The effects of the alpha2-adrenoceptor antagonist SL84.0418 and its two enantiomers, (+) deriglidole and (-)SL86.0714 on glucose… (More)
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1996
1996
Involvement of capsaicin-sensitive nerves in the regulation of glucose tolerance in diabetic rats.
The role of afferent sensory nerves in glucose tolerance and glucose stimulated insulin secretion was investigated in normal (N… (More)
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1995
1995
Alpha 2-adrenoceptors and the regulation of glucose, insulin and amylin levels in diabetic rats.
The effects of the selective alpha 2-adrenoceptor agonist UK 14.304 on glucose, insulin and amylin levels were examined in… (More)
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1995
1995
Involvement of alpha 2-adrenoceptors in metabolic and hormonal responses to a mixed meal in beagle dogs.
The effects of alpha 2-adrenoceptor blockade or activation on glucose, insulin, free fatty acids (FFA), and glycerol responses to… (More)
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1994
1994
The imidazoline SL 84.0418 shows stereoselectivity in blocking alpha 2-adrenoceptors but not ATP-sensitive K+ channels in pancreatic B-cells.
The novel alpha 2-adrenoceptor antagonist SL 84.0418 (2-(4,5-dihydro-1H-imidazol-2-yl)-1,2,4,5-tetrahydro-2-propyl-pyrrolo[3, 2,1… (More)
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