deoxyuridine triphosphate

Known as: 2'-Deoxyuridine 5'-Triphosphate, deoxy-UTP, dUTP 
A uracil nucleotide comprised of three phosphate groups esterified to the deoxyribose sugar moiety.
National Institutes of Health

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Deoxyuracil Nucleotides

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Highly Cited
2012
Highly Cited
2012
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
Oligodendrocytes, the myelin-forming glial cells of the central nervous system, maintain long-term axonal integrity. However, the… (More)
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Highly Cited
2008
Highly Cited
2008
Activating mutations in ALK provide a therapeutic target in neuroblastoma
Neuroblastoma, an embryonal tumour of the peripheral sympathetic nervous system, accounts for approximately 15% of all deaths due… (More)
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Highly Cited
2005
Highly Cited
2005
p53 Activation by Knockdown Technologies
Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to… (More)
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Highly Cited
2002
Highly Cited
2002
Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway.
Diabetic cardiomyopathy is related directly to hyperglycemia. Cell death such as apoptosis plays a critical role in cardiac… (More)
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Highly Cited
2001
Highly Cited
2001
A novel mouse model of lipotoxic cardiomyopathy.
Inherited and acquired cardiomyopathies are associated with marked intracellular lipid accumulation in the heart. To test the… (More)
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Highly Cited
1998
Highly Cited
1998
Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin.
This study determined whether retinal degeneration during diabetes includes retinal neural cell apoptosis. Image analysis of… (More)
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Highly Cited
1998
Highly Cited
1998
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
We examined the expression, activation, and cellular localization of caspase-3 (CPP32) using immunohistochemistry, immunoblots… (More)
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Highly Cited
1997
Highly Cited
1997
Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro.
The objective of this study was to determine the incidence of DNA fragmentation in human sperm, and to correlate any detected DNA… (More)
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Review
1994
Review
1994
Physiological concentrations of purines and pyrimidines
The concentrations of bases, nucleosides, and nucleosides mono-, di- and tri-phosphate are compared for about 600 published… (More)
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Highly Cited
1991
Highly Cited
1991
Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole.
The thymidylate synthase inhibitor N10-propargyl-5,8-dideazafolic acid (CB3717) inhibits the growth of human lung carcinoma A549… (More)
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