deoxyribonucleotide biosynthetic process

Known as: deoxyribonucleotide anabolism, deoxyribonucleotide synthesis, deoxyribonucleotide biosynthesis 
The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1963-2017
0246819632017

Papers overview

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2013
2013
Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence.
In normal human cells, oncogene-induced senescence (OIS) depends on induction of DNA damage response. Oxidative stress and… (More)
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2008
2008
Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice.
Deficient enzymatic activity of the mitochondrial deoxyribonucleoside kinases deoxyguanosine kinase (DGUOK) or thymidine kinase 2… (More)
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2008
2008
The GlxR regulon of the amino acid producer Corynebacterium glutamicum: in silico and in vitro detection of DNA binding sites of a global transcription regulator.
The glxR (cg0350) gene of Corynebacterium glutamicum ATCC 13032 encodes a DNA-binding transcription regulator of the CRP/FNR… (More)
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Highly Cited
2006
Highly Cited
2006
Mitoferrin is essential for erythroid iron assimilation
Iron has a fundamental role in many metabolic processes, including electron transport, deoxyribonucleotide synthesis, oxygen… (More)
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Highly Cited
2006
Highly Cited
2006
A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli.
We present evidence for a complex regulatory interplay between the initiation of DNA replication and deoxyribonucleotide… (More)
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Highly Cited
2001
Highly Cited
2001
Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems.
Thioredoxin (Trx) and glutathione (GSH) systems are considered to be two major redox systems in animal cells. They are reduced by… (More)
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2001
2001
Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.
Trypanosoma brucei, the causative agent of African sleeping sickness, synthesizes deoxyribonucleotides via a classical eukaryotic… (More)
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1994
1994
Two additional glutaredoxins exist in Escherichia coli: glutaredoxin 3 is a hydrogen donor for ribonucleotide reductase in a thioredoxin/glutaredoxin 1 double mutant.
Thioredoxin (Trx) and glutaredoxin (Grx1) are hydrogen donors for ribonucleotide reductase, the key enzyme for… (More)
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1990
1990
Thioredoxin or glutaredoxin in Escherichia coli is essential for sulfate reduction but not for deoxyribonucleotide synthesis.
We have shown previously that Escherichia coli cells constructed to lack both thioredoxin and glutaredoxin are not viable unless… (More)
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1966
1966
Regulation of mammalian deoxyribonucleotide biosynthesis by nucleotides as activators and inhibitors.
The effects of several nucleoside triphosphates as activators and inhibitors of the enzymic reduction of ribonucleoside… (More)
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