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demoxepam
Known as:
7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Benzodiazepines
Demoxepam:MCnc:Pt:Ser/Plas:Qn
Demoxepam:PrThr:Pt:Ser/Plas:Ord
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
A rapid and simple determination of A77 1726 in human serum by high-performance liquid chromatography and its application for optimization of leflunomide therapy.
E. V. van Roon
,
J. Yska
,
J. Raemaekers
,
T. Jansen
,
M. V. van Wanrooy
,
J. Brouwers
Journal of pharmaceutical and biomedical analysis
2004
Corpus ID: 27875064
Highly Cited
1995
Highly Cited
1995
Immunoassay detection of benzodiazepines and benzodiazepine metabolites in blood.
W. Huang
,
D. Moody
Journal of analytical toxicology
1995
Corpus ID: 20761059
We evaluated the capability of commercially available benzodiazepine immunoassays from four vendors (Abuscreen radioimmunoassay…
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Highly Cited
1984
Highly Cited
1984
The decomposition of benzodiazepines during analysis by capillary gas chromatography/mass spectrometry.
J. R. Joyce
,
T. Bal
,
R. Ardrey
,
H. M. Stevens
,
A. Moffat
Biomedical mass spectrometry
1984
Corpus ID: 24474446
A capillary gas chromatography column directly interfaced to a mass spectrometer was used for the analysis of sixteen…
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1984
1984
Assay of chlordiazepoxide and demoxepam in chlordiazepoxide formulations by difference spectrophotometry.
A. G. Davidson
Journal of pharmaceutical sciences
1984
Corpus ID: 35532010
Rapid difference spectrophotometric methods for chlordiazepoxide and demoxepam in chlordiazepoxide formulations are described…
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1980
1980
STRUCTURE AND PHOTOBIOLOGICAL ACTIVITY OF 7‐CHLORO‐1,4‐BENZODIAZEPINES. STUDIES ON THE PHOTOTOXIC EFFECTS OF CHLORDIAZEPOXIDE, DESMETHYLCHLORDIAZEPOXIDE AND DEMOXEPAM USING A BACTERIAL INDICATOR…
P. Cornelissen
,
G. M. Beijersbergen
,
V. Henegouwen
,
G. Mohn
Photochemistry and photobiology
1980
Corpus ID: 26518099
The photobiological activity of chlordiazepoxide, an active ingredient of the drug Librium, which is known to induce phototoxic…
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1977
1977
Determination of chlordiazepoxide, diazepam, and their major metabolites in blood or plasma by spectrophotodensitometry.
N. Stronjny
,
K. Bratin
,
M. Brooks
,
J. D. de Silva
Journal of chromatography
1977
Corpus ID: 38821648
1976
1976
Kinetics and mechanisms of hydrolysis of 1,4-benzodiazepines I: chlordiazepoxide and demoxepam.
W. Han
,
G. Yakatan
,
D. D. Maness
Journal of pharmaceutical sciences
1976
Corpus ID: 27444877
Differential absorbance spectroscopy was successfully used to follow the hydrolysis kinetics of chlordiazepoxide and demoxepam…
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Highly Cited
1975
Highly Cited
1975
Clinical Pharmacokinetics of Chlordiazepoxide
D. Greenblatt
,
R. Shader
,
S. Macleod
,
E. Sellers
Psychopharmacology bulletin
1975
Corpus ID: 8007780
SummaryChlordiazepoxide was the first benzodiazepine derivative made available for clinical use. The metabolic pathway of…
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1972
1972
Metabolites of demoxepam, a chlordiazepoxide metabolite, in man.
M. A. Schwartz
,
E. Postma
Journal of pharmaceutical sciences
1972
Corpus ID: 29004353
The biotransformation of demoxepam, 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide, was studied in two subjects…
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1971
1971
Biological half-life of chlordiazepoxide and its metabolite, demoxepam, in man.
M. A. Schwartz
,
E. Postma
,
Z. Gaut
Journal of pharmaceutical sciences
1971
Corpus ID: 21070759
In a crossover study, single 20-mg, oral doses of chlordiazepoxide and one of its metabolites, demoxepam, were administered to…
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