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demoxepam
Known as:
7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (1)
Benzodiazepines
Demoxepam:MCnc:Pt:Ser/Plas:Qn
Demoxepam:PrThr:Pt:Ser/Plas:Ord
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1986
1986
Simplified high performance liquid chromatographic method for the determination of clonazepam and other benzodiazepines in serum.
V. Haver
,
W. H. Porter
,
L. D. Dorie
,
J. Lea
Therapeutic Drug Monitoring
1986
Corpus ID: 30444973
A convenient and sensitive high performance liquid chromatographic method was developed for determination of clonazepam in serum…
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1982
1982
Liquid chromatographic determination of chlordiazepoxide and metabolites in plasma.
M. Divoll
,
D. Greenblatt
,
R. Shader
Pharmacology
1982
Corpus ID: 46800486
Sensitive quantitation of chlordiazepoxide and its two principal metabolites, desmethylchlordiazepoxide and demoxepam, in human…
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1980
1980
A sensitive benzodiazepine radioimmunoassay of broad specificity.
K. Robinson
,
M. Rutterford
,
R. Smith
The Journal of pharmacy and pharmacology
1980
Corpus ID: 35025867
Four benzodiazepine radioimmunoassays are described, the most sensitive of which can detect sub-therapeutic levels of bromazepam…
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1978
1978
The application of HPLC to the determination of some 1,4 benzodiazepines and their metabolites in plasma.
G. Skellern
,
J. Meier
,
B. Knight
,
B. Whiting
British Journal of Clinical Pharmacology
1978
Corpus ID: 21780782
1 A high pressure liquid chromatographic (HPLC) assay has been developed for the measurement of chlordiazepoxide and its…
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Review
1978
Review
1978
Clinical pharmacokinetics of chlordiazepoxide.
D. Greenblatt
,
R. Shader
,
S. Macleod
,
E. Sellers
Clinical Pharmacokinetics
1978
Corpus ID: 38441368
Chlordiazepoxide was the first benzodiazepine derivative made available for clinical use. The metabolic pathway of…
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1978
1978
[Effect of benzodiazepines on the fluorescence of tryptophan in human serum albumin, hemoglobin and erythrocyte ghosts].
B. Terhaag
,
E. Ackermann
Acta biologica et medica Germanica
1978
Corpus ID: 39200945
The binding of chlorodiazepoxide, demethyl-chlorodiazepoxide, demoxepam, medazepam, diazepam and oxazepam was investigated on…
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1976
1976
Kinetics and mechanisms of hydrolysis of 1,4-benzodiazepines I: chlordiazepoxide and demoxepam.
W. Han
,
G. Yakatan
,
D. Maness
Journal of Pharmacy and Science
1976
Corpus ID: 27444877
Differential absorbance spectroscopy was successfully used to follow the hydrolysis kinetics of chlordiazepoxide and demoxepam…
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1972
1972
Metabolites of demoxepam, a chlordiazepoxide metabolite, in man.
M. A. Schwartz
,
E. Postma
Journal of Pharmacy and Science
1972
Corpus ID: 29004353
The biotransformation of demoxepam, 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide, was studied in two subjects…
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1972
1972
Quinazolines and 1,4-benzodiazepines. 55. Synthesis of two metabolites of demoxepam isolated from the dog.
E. E. García
,
L. E. Benjamin
,
R. Fryer
,
L. Sternbach
Journal of Medicinal Chemistry
1972
Corpus ID: 33685103
1971
1971
Metabolism of demoxepam, a chlordiazepoxide metabolite, in the dog.
M. A. Schwartz
,
E. Postma
,
S. Kolis
Journal of Pharmacy and Science
1971
Corpus ID: 32930813
Abstract The pharmacokinetic evaluation of the disposition of intravenous and oral doses of demoxepam, 7-chloro-1,3-dihydro-5…
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